Rabbit anti-Human LCN8 Polyclonal Antibody | anti-LCN8 antibody

LCN8, CT (LCN8, LCN5, Epididymal-specific lipocalin-8) (PE)

Cat. Num. AAA6315513

• Gene Names: LCN8; EP17; LCN5
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LCN8; Polyclonal Antibody; CT (LCN8; LCN5; Epididymal-specific lipocalin-8) (PE); Epididymal-specific lipocalin-8; anti-LCN8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-LCN8 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LCN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-140 amino acids from the C-terminal region of human LCN8.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(LCN8 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the LCN8 antibody detected the LCN8 protein (arrow).)

Related Product Information for anti-LCN8 antibody

Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).

Product Categories/Family for anti-LCN8 antibody

Antibodies; Transport Proteins

References

Suzuki, K., et al. Gene 339, 49-59 (2004): Humphray, S.J., et al. Nature 429(6990):369-374(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 62988357
• NCBI GeneID: 138307
• NCBI Accession #: NP_848564.2
• NCBI GenBank Nucleotide #: NM_178469.3
• UniProt Accession #: Q6JVE9; Q5T5R4; A1L4A8; A6NMN9
• Molecular Weight: 17,254 Da
• NCBI Official Full Name: epididymal-specific lipocalin-8
• NCBI Official Synonym Full Names: lipocalin 8
• NCBI Official Symbol: LCN8
• NCBI Official Synonym Symbols: EP17; LCN5
• NCBI Protein Information: epididymal-specific lipocalin-8
• UniProt Protein Name: Epididymal-specific lipocalin-8
• Protein Family: Epididymal-specific lipocalin
• UniProt Gene Name: LCN8
• UniProt Synonym Gene Names: LCN5
• UniProt Entry Name: LCN8_HUMAN

NCBI Description

Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]

Uniprot Description

LCN8: May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. Belongs to the calycin superfamily. Lipocalin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: extracellular region

Biological Process: transport; response to hormone stimulus