Western Blot (WB)
(LCE1A Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the LCE1A antibody detected the LCE1A protein (arrow).)
Rabbit anti-Human LCE1A Polyclonal Antibody | anti-LCE1A antibody
LCE1A Antibody (C-term)
Gene Names
LCE1A; LEP1
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
LCE1A; Polyclonal Antibody; LCE1A Antibody (C-term); Late cornified envelope protein 1A; Late envelope protein 1; LEP1; anti-LCE1A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This LCE1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the C-terminal region of human LCE1A.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.48 (varies by lot)
Sequence Positions
54-83
Sequence Length
110
Applicable Applications for anti-LCE1A antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(LCE1A Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the LCE1A antibody detected the LCE1A protein (arrow).)
Western Blot (WB)
(LCE1A Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the LCE1A antibody detected the LCE1A protein (arrow).)
Immunohistochemistry (IHC)
(LCE1A antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LCE1A antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(LCE1A antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LCE1A antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-LCE1A antibody
LCE1A belongs to the late cornified envelope (LCE) gene
cluster within the epidermal differentiation complex (EDC) on
chromosome 1. The LCE cluster contains multiple conserved genes
that encode stratum corneum proteins, and these genes are expressed
relatively late during fetal assembly of the skin cornified
envelope (Jackson et al., 2005 [PubMed 15854049]). For further
information on the LCE gene cluster, see GENE FAMILY
below.
cluster within the epidermal differentiation complex (EDC) on
chromosome 1. The LCE cluster contains multiple conserved genes
that encode stratum corneum proteins, and these genes are expressed
relatively late during fetal assembly of the skin cornified
envelope (Jackson et al., 2005 [PubMed 15854049]). For further
information on the LCE gene cluster, see GENE FAMILY
below.
Product Categories/Family for anti-LCE1A antibody
References
Jackson, B., et al. J. Invest. Dermatol. 124(5):1062-1070(2005)
Marshall, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98(23):13031-13036(2001)
Marshall, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98(23):13031-13036(2001)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10982
NCBI Official Full Name
late cornified envelope protein 1A
NCBI Official Synonym Full Names
late cornified envelope 1A
NCBI Official Symbol
LCE1A
NCBI Official Synonym Symbols
LEP1
NCBI Protein Information
late cornified envelope protein 1A
UniProt Protein Name
Late cornified envelope protein 1A
Protein Family
UniProt Gene Name
LCE1A
UniProt Synonym Gene Names
LEP1
UniProt Entry Name
LCE1A_HUMAN
NCBI Description
LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 [PubMed 15854049]). For further information on the LCE gene cluster, see GENE FAMILY below.[supplied by OMIM, Feb 2009]
Uniprot Description
LCE1A: Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.
Chromosomal Location of Human Ortholog: 1q21.3
Research Articles on LCE1A
Similar Products
Product Notes
The LCE1A lce1a (Catalog #AAA9202011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 54-83. The LCE1A Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LCE1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the LCE1A lce1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LCE1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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