Western Blot (WB)
(LAX1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LAX1 antibody detected the LAX1 protein (arrow).)
Rabbit anti-Human LAX1 Polyclonal Antibody | anti-LAX1 antibody
LAX1 Antibody (C-term)
Gene Names
LAX1; LAX
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
LAX1; Polyclonal Antibody; LAX1 Antibody (C-term); Lymphocyte transmembrane adapter 1; Linker for activation of X cells; Membrane-associated adapter protein LAX; LAX; anti-LAX1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This LAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the C-terminal region of human LAX1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.3 (varies by lot)
Sequence Positions
369-398
Sequence Length
382
Applicable Applications for anti-LAX1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(LAX1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LAX1 antibody detected the LAX1 protein (arrow).)
Western Blot (WB)
(LAX1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LAX1 antibody detected the LAX1 protein (arrow).)
Related Product Information for anti-LAX1 antibody
LAX1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Product Categories/Family for anti-LAX1 antibody
References
Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)
Shapiro, M.J., et al. J. Immunol. 181(10):7055-7061(2008)
Zhu, M., et al. J. Immunol. 174(9):5612-5619(2005)
Zhu, M., et al. J. Biol. Chem. 277(48):46151-46158(2002)
Shapiro, M.J., et al. J. Immunol. 181(10):7055-7061(2008)
Zhu, M., et al. J. Immunol. 174(9):5612-5619(2005)
Zhu, M., et al. J. Biol. Chem. 277(48):46151-46158(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44085
NCBI Official Full Name
lymphocyte transmembrane adapter 1 isoform b
NCBI Official Synonym Full Names
lymphocyte transmembrane adaptor 1
NCBI Official Symbol
LAX1
NCBI Official Synonym Symbols
LAX
NCBI Protein Information
lymphocyte transmembrane adapter 1
UniProt Protein Name
Lymphocyte transmembrane adapter 1
Protein Family
UniProt Gene Name
LAX1
UniProt Synonym Gene Names
LAX
UniProt Entry Name
LAX1_HUMAN
Uniprot Description
LAX1: Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: Golgi apparatus; membrane; cytoplasm; plasma membrane; integral to membrane; lipid raft
Molecular Function: protein binding; SH2 domain binding; protein kinase binding
Biological Process: antigen receptor-mediated signaling pathway; B cell activation; immunoglobulin secretion; immune response; negative regulation of T cell activation; inactivation of MAPK activity
Research Articles on LAX1
Similar Products
Product Notes
The LAX1 lax1 (Catalog #AAA9212756) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 369-398. The LAX1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LAX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the LAX1 lax1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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