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Western Blot (WB)
(Western Blot: Lane1: Mouse Liver Tissue; Lane2: Mouse Placenta Tissue; Lane3: Mouse Spleen Tissue.)
Rabbit anti-Mouse Latent Transforming Growth Factor Beta Binding Protein 1 Polyclonal Antibody | anti-LTBP1 antibody
Polyclonal Antibody to Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1)
Gene Names
Ltbp1; Tgfb; Ltbp-1; Ltbp1L; 9830146M04; b2b1000Clo; 9430031G15Rik; TGF-beta1-BP-1
Reactivity
Mouse
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Latent Transforming Growth Factor Beta Binding Protein 1; Polyclonal Antibody; Polyclonal Antibody to Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1); anti-LTBP1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against LTBP1. It has beenselected for its ability to recognize LTBP1 in immunohistochemical staining andwestern blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
500ug/ml (varies by lot)
Sequence Length
1300
Applicable Applications for anti-LTBP1 antibody
WB; IHC; ICC; IP.
Application Notes
Western blotting: 0.5-2 ug/mL;1:210-860
Immunohistochemistry: 5-20 ug/mL;1:21-86
Immunocytochemistry: 5-20 ug/mL;1:21-86
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 5-20 ug/mL;1:21-86
Immunocytochemistry: 5-20 ug/mL;1:21-86
Optimal working dilutions must be determined by end user.
Organism Species
Mus musculus (Mouse)
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant LTBP1 (Asp1415~Glu1712) expressed in E.coli
Cross Reactivity
Mouse
Conjugate
No Conjugate
Immunogen
Recombinant LTBP1 (Asp1415~Glu1712) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2063432
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Lane1: Mouse Liver Tissue; Lane2: Mouse Placenta Tissue; Lane3: Mouse Spleen Tissue.)
Western Blot (WB)
(Western Blot: Lane1: Mouse Liver Tissue; Lane2: Mouse Placenta Tissue; Lane3: Mouse Spleen Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant LTBP1, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant LTBP1, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Intestine Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Intestine Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Heart Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Heart Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Skeletal Muscle Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Skeletal Muscle Tissue)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
latent-transforming growth factor beta-binding protein 1 isoform 7
NCBI Official Synonym Full Names
latent transforming growth factor beta binding protein 1
NCBI Official Symbol
Ltbp1
NCBI Official Synonym Symbols
Tgfb; Ltbp-1; Ltbp1L; 9830146M04; b2b1000Clo; 9430031G15Rik; TGF-beta1-BP-1
NCBI Protein Information
latent-transforming growth factor beta-binding protein 1
UniProt Protein Name
Latent-transforming growth factor beta-binding protein 1
Protein Family
UniProt Gene Name
Ltbp1
UniProt Synonym Gene Names
LTBP-1; TGF-beta1-BP-1
Uniprot Description
LTBP1: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). Belongs to the LTBP family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Chaperone; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17|17 E2
Cellular Component: cell soma; cytoplasm; dendrite; extracellular matrix; extracellular region; extracellular space; microfibril; mitochondrion; perinuclear region of cytoplasm; protein complex; proteinaceous extracellular matrix
Molecular Function: calcium ion binding; growth factor binding; microfibril binding; transforming growth factor beta binding
Biological Process: positive regulation of collagen biosynthetic process; transforming growth factor beta receptor signaling pathway
Research Articles on LTBP1
Similar Products
Product Notes
The LTBP1 ltbp1 (Catalog #AAA2027697) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Latent Transforming Growth Factor Beta Binding Protein 1 (LTBP1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Latent Transforming Growth Factor Beta Binding Protein 1 can be used in a range of immunoassay formats including, but not limited to, WB; IHC; ICC; IP. Western blotting: 0.5-2 ug/mL;1:210-860 Immunohistochemistry: 5-20 ug/mL;1:21-86 Immunocytochemistry: 5-20 ug/mL;1:21-86 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the LTBP1 ltbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Latent Transforming Growth Factor Beta Binding Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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