Rabbit anti-Human, Mouse LAPTM5 Polyclonal Antibody | anti-LAPTM5 antibody

LAPTM5 Rabbit pAb

Cat. Num. AAA9143142

• Gene Names: LAPTM5; CLAST6
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Affinity purification
• Synonyms: LAPTM5; Polyclonal Antibody; LAPTM5 Rabbit pAb; CLAST6; anti-LAPTM5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Applicable Applications for anti-LAPTM5 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant protein of human LAPTM5.
• Positive Samples: K562, 293T, mouse thymus, mouse lung
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using LAPTM5 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (RM00020).Exposure time: 60s.)

NCBI and Uniprot Product Information

• NCBI GI #: 5803056
• NCBI GeneID: 7805
• NCBI Accession #: NP_006753.1
• NCBI GenBank Nucleotide #: NM_006762.2
• UniProt Accession #: Q13571; Q13240; Q14698; Q3KP54
• Molecular Weight: 29,937 Da
• NCBI Official Full Name: lysosomal-associated transmembrane protein 5
• NCBI Official Synonym Full Names: lysosomal protein transmembrane 5
• NCBI Official Symbol: LAPTM5
• NCBI Official Synonym Symbols: CLAST6
• NCBI Protein Information: lysosomal-associated transmembrane protein 5; retinoic acid-inducible E3 protein; human retinoic acid-inducible E3 protein; CD40-ligand-activated specific transcripts; lysosomal multispanning membrane protein 5; lysosomal-associated multitransmembrane pro
• UniProt Protein Name: Lysosomal-associated transmembrane protein 5
• Protein Family: Lysosomal-associated transmembrane protein
• UniProt Gene Name: LAPTM5
• UniProt Synonym Gene Names: KIAA0085
• UniProt Entry Name: LAPM5_HUMAN

NCBI Description

This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis. [provided by RefSeq, Feb 2009]

Uniprot Description

Function: May have a special functional role during embryogenesis and in adult hematopoietic cells. Ref.1

Subunit structure: Binds to ubiquitin. Ref.1

Subcellular location: Lysosome membrane; Multi-pass membrane protein Ref.1.

Tissue specificity: Preferentially expressed in adult hematopoietic tissues. High levels in lymphoid and myeloid tissues. Highly expressed in peripheral blood leukocytes, thymus, spleen and lung, followed by placenta, liver and kidney. Ref.1

Induction: By retinoic acid.

Sequence similarities: Belongs to the LAPTM4/LAPTM5 transporter family.

Sequence caution: The sequence BAA07643.1 differs from that shown. Reason: Erroneous initiation.