Western Blot (WB)
(Western Blot analysis of RAW HepG2 A549 cells using Laminin alpha-5 Polyclonal Antibody)
Rabbit anti-Human, Mouse LAMA5 Polyclonal Antibody | anti-LAMA5 antibody
LAMA5 Antibody
IHC: 1:100-1:300
ELISA: 1:20000
Western Blot (WB)
(Western Blot analysis of RAW HepG2 A549 cells using Laminin alpha-5 Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of RAW HepG2 A549 cells using Laminin alpha-5 Polyclonal Antibody)
NCBI and Uniprot Product Information
NCBI Description
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Protein type: Secreted, signal peptide; Secreted; Extracellular matrix; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 20q13.2-q13.3
Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus
Molecular Function: integrin binding; structural molecule activity
Biological Process: integrin-mediated signaling pathway; regulation of cell adhesion; focal adhesion formation; endothelial cell differentiation; extracellular matrix organization and biogenesis; muscle development; cell migration; regulation of embryonic development; cell recognition; cytoskeleton organization and biogenesis; regulation of cell migration; regulation of cell proliferation; odontogenesis of dentine-containing teeth; cell proliferation; extracellular matrix disassembly; embryonic development; morphogenesis of embryonic epithelium; hair follicle development; ureteric bud branching; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; lung development
Research Articles on LAMA5
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Product Notes
The LAMA5 lama5 (Catalog #AAA7118396) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LAMA5 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LAMA5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:100-1:300 ELISA: 1:20000. Researchers should empirically determine the suitability of the LAMA5 lama5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMA5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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