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Western Blot (WB) (Western blot analysis of placental lactogen using recombinant HPL. Lane 1: 10 ng Lane 2: 50 ng Lane 3: 100 ng)

Rabbit anti-Human Lactogen, Placental Polyclonal Antibody | anti-LTF antibody

Lactogen, Placental (PL, hPL, Choriomammotropin, Chorionic Somatomammotropin A, CSA, Chorionic Somatomammotropin Hormone 1, CSH1, CS1, CSH2, CSMT, FLJ75407, Somatotropin Precursor)

Gene Names
LTF; LF; HLF2; GIG12
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Purified by affinity chromatography.
Synonyms
Lactogen; Placental; Polyclonal Antibody; Placental (PL; hPL; Choriomammotropin; Chorionic Somatomammotropin A; CSA; Chorionic Somatomammotropin Hormone 1; CSH1; CS1; CSH2; CSMT; FLJ75407; Somatotropin Precursor); Anti -Lactogen; anti-LTF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Placental Lactogen.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosol, 30% glycerol.
Applicable Applications for anti-LTF antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-4ug/ml
Immunogen
Recombinant human Placental Lactogen expressed in E. coli.
Positive Control
Recombinant placental lactogen (HPL)
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of placental lactogen using recombinant HPL. Lane 1: 10 ng Lane 2: 50 ng Lane 3: 100 ng)

Western Blot (WB) (Western blot analysis of placental lactogen using recombinant HPL. Lane 1: 10 ng Lane 2: 50 ng Lane 3: 100 ng)
Related Product Information for anti-LTF antibody
Human Placental Lactogen (HPL), also called human chorionic somatomammotropin, is a polypeptide placental hormone. Its structure and function is similar to that of growth hormone. It modifies the metabolic state of the mother during pregnancy to facilitate the energy supply of the fetus. Recombinant human Placental Lactogen is a 22.3kD protein.
Product Categories/Family for anti-LTF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
78,384 Da
NCBI Official Full Name
lactoferrin
NCBI Official Synonym Full Names
lactotransferrin
NCBI Official Symbol
LTF
NCBI Official Synonym Symbols
LF; HLF2; GIG12
NCBI Protein Information
lactotransferrin; talalactoferrin; OTTHUMP00000209779; OTTHUMP00000209780; OTTHUMP00000209781; neutrophil lactoferrin; growth-inhibiting protein 12
UniProt Protein Name
Growth-inhibiting protein 12
Protein Family
UniProt Gene Name
GIG12
UniProt Entry Name
Q5DSM0_HUMAN

NCBI Description

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Uniprot Description

LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter.

Protein type: EC 3.4.21.-; Protease; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: extracellular space; specific granule; cytoplasm; extracellular region; nucleus; secretory granule

Molecular Function: heparin binding; protein serine/threonine kinase activator activity; protein binding; DNA binding; ferric iron binding; iron ion binding; serine-type endopeptidase activity

Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; interaction with host; ossification; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; positive regulation of toll-like receptor 4 signaling pathway; antifungal humoral response; proteolysis; iron ion transport; humoral immune response; regulation of cytokine production; activation of NF-kappaB transcription factor; retinal homeostasis; positive regulation of osteoblast differentiation; innate immune response in mucosa; negative regulation of viral genome replication; response to host immune response; positive regulation of osteoblast proliferation; antibacterial humoral response; regulation of tumor necrosis factor production; negative regulation of viral reproduction; negative regulation of ATPase activity; iron assimilation by chelation and transport; negative regulation of apoptosis

Research Articles on LTF

Similar Products

Product Notes

The LTF gig12 (Catalog #AAA625351) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Lactogen, Placental (PL, hPL, Choriomammotropin, Chorionic Somatomammotropin A, CSA, Chorionic Somatomammotropin Hormone 1, CSH1, CS1, CSH2, CSMT, FLJ75407, Somatotropin Precursor) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lactogen, Placental can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.5-4ug/ml. Researchers should empirically determine the suitability of the LTF gig12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lactogen, Placental, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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