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Placental Lactogen/CSH1 Recombinant Protein | CSH1 recombinant protein
Placental Lactogen/CSH1 Protein, Human, Recombinant (His Tag)
Gene Names
CSH1; PL; CSA; CS-1; CSMT; hCS-A
Purity
>87% as determined by SDS-PAGE
Synonyms
Placental Lactogen/CSH1; Placental Lactogen/CSH1 Protein; Human; Recombinant (His Tag); Human Placental Lactogen/CSH1 Protein (His Tag); CS-1 Protein; CSA Protein; CSMT Protein; hCS-1 Protein; hCS-A Protein; PL Protein; chorionic somatomammotropin hormone 1 (placental lactogen); CSH1 recombinant protein
Host
HEK293 Cells
Purity/Purification
>87% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Phe217
Species
Human
Endotoxin
<1.0EU per ug of the protein as determined by the LAL method
Predicted N Terminal
Val 27
Tag
C-His
Protein Construction
A DNA sequence encoding the human CSH1 (NP_001308.1)(Met 1-Phe 217) was expressed, fused with a polyhistidine tag at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
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SDS-Page
Related Product Information for CSH1 recombinant protein
Background: Chorionic somatomammotropin hormone, also known as Choriomammotropin, Lactogen, Placental lactogen and CSH1, is a secreted protein which belongs to thesomatotropin/prolactin family. CSH1 is produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. The CSH1 gene is member of the GH gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. Genomic alterations in the GH cluster are well known, causing different phenotypes depending on the size of the deletion and the genes involved. The increased prevalence of hemizygosity of CSH1 in population in comparison to controls indicates a role for CSH1 haploinsufficiency in the etiology of growth retardation. Investigation of CSH1 deletions in further SRS and growth retarded patients will enable us to establish under which circumstances haploinsufficiency of CSH1 is likely to result in clinical changes.
Product Categories/Family for CSH1 recombinant protein
References
Prager,S. et al., 2003,Genet Test. 7 (3):259-63. Singleton, DR. et al., 2004, Microbiology. 150 (Pt 2): 285-92. Chen,Y. et al., 2008, Cancer Res. 68 (23):9729-34.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,020 Da
NCBI Official Full Name
chorionic somatomammotropin hormone
NCBI Official Synonym Full Names
chorionic somatomammotropin hormone 1 (placental lactogen)
NCBI Official Symbol
CSH1
NCBI Official Synonym Symbols
PL; CSA; CS-1; CSMT; hCS-A
NCBI Protein Information
chorionic somatomammotropin hormone; choriomammotropin; placental lactogen; chorionic somatomammotropin A
UniProt Protein Name
Chorionic somatomammotropin hormone
Protein Family
UniProt Gene Name
CSH1
UniProt Synonym Gene Names
Choriomammotropin; PL
UniProt Entry Name
CSH_HUMAN
Uniprot Description
CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q24.2
Cellular Component: extracellular region
Molecular Function: hormone activity; metal ion binding
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Product Notes
The CSH1 csh1 (Catalog #AAA8120867) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Phe21 7. It is sometimes possible for the material contained within the vial of "Placental Lactogen/CSH1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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