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Western Blot (WB) (L3MBTL3 Antibody (N-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the L3MBTL3 antibody detected the L3MBTL3 protein (arrow).)

Rabbit anti-Human L3MBTL3 Polyclonal Antibody | anti-L3MBTL3 antibody

L3MBTL3 Antibody (N-term)

Gene Names
L3MBTL3; MBT1; MBT-1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
L3MBTL3; Polyclonal Antibody; L3MBTL3 Antibody (N-term); Lethal(3)malignant brain tumor-like protein 3; H-l(3)mbt-like protein 3; L(3)mbt-like protein 3; MBT-1; KIAA1798; MBT1; anti-L3MBTL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This L3MBTL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-116 amino acids from the N-terminal region of human L3MBTL3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.39 (varies by lot)
Sequence Positions
90-116
Sequence Length
755
Applicable Applications for anti-L3MBTL3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(L3MBTL3 Antibody (N-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the L3MBTL3 antibody detected the L3MBTL3 protein (arrow).)

Western Blot (WB) (L3MBTL3 Antibody (N-term) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the L3MBTL3 antibody detected the L3MBTL3 protein (arrow).)
Related Product Information for anti-L3MBTL3 antibody
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity).
Product Categories/Family for anti-L3MBTL3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
88337
NCBI Official Full Name
lethal(3)malignant brain tumor-like protein 3 isoform b
NCBI Official Synonym Full Names
l(3)mbt-like 3 (Drosophila)
NCBI Official Symbol
L3MBTL3
NCBI Official Synonym Symbols
MBT1; MBT-1
NCBI Protein Information
lethal(3)malignant brain tumor-like protein 3
UniProt Protein Name
Lethal(3)malignant brain tumor-like protein 3
UniProt Gene Name
L3MBTL3
UniProt Synonym Gene Names
KIAA1798; MBT1; H-l(3)mbt-like protein 3; L(3)mbt-like protein 3
UniProt Entry Name
LMBL3_HUMAN

Uniprot Description

L3MBTL3: a Polycomb group (PcG) protein that regulates the maturation of myeloid progenitor cells. May influence myelopoiesis by transiently enhancing p57(KIP2) expression levels. PcG proteins participate in DNA-binding complexes with gene-repressing activity, many of which have been highlighted for their involvement in hematopoiesis. A member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. Contains a SAM domain, a common protein modules found in eukaryotic proteomes. Many SAM domains have been shown to form helical polymer structures. May create large protein complexes in the cell. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 6q23

Cellular Component: nucleus

Biological Process: erythrocyte maturation; macrophage differentiation; regulation of transcription, DNA-dependent; granulocyte differentiation; transcription, DNA-dependent; chromatin modification

Research Articles on L3MBTL3

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Product Notes

The L3MBTL3 l3mbtl3 (Catalog #AAA9201532) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 90-116. The L3MBTL3 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's L3MBTL3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the L3MBTL3 l3mbtl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "L3MBTL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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