Western Blot (WB)
(All lanes: Major capsid protein L1 antibody at 2ug/ml+293T whole cell lysateSecondary)
Rabbit anti-Virus L1 Polyclonal Antibody | anti-L1 antibody
L1 Polyclonal Antibody
Reactivity
Virus
Applications
Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
L1; Polyclonal Antibody; L1 Polyclonal Antibody; anti-L1 antibody
Host
Rabbit
Reactivity
Virus
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total L1 polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
568
Applicable Applications for anti-L1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:1000
Immunogen
Recombinant HPV18 Major capsid protein L1 protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Western Blot (WB)
(All lanes: Major capsid protein L1 antibody at 2ug/ml+293T whole cell lysateSecondary)
Western Blot (WB)
(All lanes: Major capsid protein L1 antibody at 2ug/ml+293T whole cell lysateSecondary)
Related Product Information for anti-L1 antibody
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on the basement membrane to provide initial virion attachment to target cells.Basement membrane is exposed only after epithelium trauma. Additionally, the alpha6 integrin complexed with either beta1 or beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, integrin complexed with beta4 integrin has been proposed to act as a coreceptor recognized by L1. Once attached, the virion enters the host cell via clathrin-mediated endocytosis and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus.Encapsulates the genomic DNA together with protein L2.
Product Categories/Family for anti-L1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,624 Da
NCBI Official Full Name
L1 protein
NCBI Official Symbol
L1
NCBI Protein Information
major capsid L1 protein
UniProt Protein Name
Major capsid protein L1
Protein Family
UniProt Gene Name
L1
UniProt Entry Name
VL1_HPV18
Uniprot Description
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Similar Products
Product Notes
The L1 l1 (Catalog #AAA9415947) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The L1 Polyclonal Antibody reacts with Virus and may cross-react with other species as described in the data sheet. AAA Biotech's L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000. Researchers should empirically determine the suitability of the L1 l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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