Rabbit Kv1.5 Polyclonal Antibody
Kv1.5 (Kcna5, Voltage-gated, Delayed-rectifier Potassium Channel)
Reactivity
Equine, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Kv1.5; Polyclonal Antibody; Kv1.5 (Kcna5; Voltage-gated; Delayed-rectifier Potassium Channel); Anti -Kv1.5 (Kcna5; anti-Kv1.5 antibody
Host
Rabbit
Reactivity
Equine, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse Kv1.5. Species Crossreactivity: Rat, equine.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 5% sucrose, 0.05% sodium azide.
Sequence
HRETD HEEQA ALKEE QGIQR RESGL DTGGQ RKVSC SKASF HKTGG PLEST DSIRR GSCPL EKCHL KAKSN VDLRR SLYAL CLDTS RETDL
Applicable Applications for anti-Kv1.5 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation.
Dilution: Western Blot: 1:200-1:400 (Rat brain membranes).
Immunohistochemistry: Rat brain sections
Note: Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal dilution determined by the researcher.
Dilution: Western Blot: 1:200-1:400 (Rat brain membranes).
Immunohistochemistry: Rat brain sections
Note: Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal dilution determined by the researcher.
Immunogen
GST Fusion protein and a C-terminal portion (aa513-602) of mouse Kv1.5 (Accession # Q61762). Epitope: HRETD HEEQA ALKEE QGIQR RESGL DTGGQ RKVSC SKASF HKTGG PLEST DSIRR GSCPL EKCHL KAKSN VDLRR SLYAL CLDTS RETDL
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Kv1.5 antibody
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potasssium ions may pass in accordance with their electrochemical gradient. May play a role in regulating the secretion of insulin in normal pancreatic islets.
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes-shaker, shaw, shab, and shal-have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome.
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes-shaker, shaw, shab, and shal-have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome.
Product Categories/Family for anti-Kv1.5 antibody
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Product Notes
The Kv1.5 (Catalog #AAA613549) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Kv1.5 (Kcna5, Voltage-gated, Delayed-rectifier Potassium Channel) reacts with Equine, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Kv1.5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Dilution: Western Blot: 1:200-1:400 (Rat brain membranes). Immunohistochemistry: Rat brain sections Note: Dilutions should be made using a carrier protein such as BSA (1-3%). Optimal dilution determined by the researcher. Researchers should empirically determine the suitability of the Kv1.5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: HRETD HEEQA ALKEE QGIQR RESGL DTGGQ RKVSC SKASF HKTGG PLEST DSIRR GSCPL EKCHL KAKSN VDLRR SLYAL CLDTS RETDL. It is sometimes possible for the material contained within the vial of "Kv1.5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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