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Western Blot (WB) (Western Blot analysis of Jurkat cells with Ku-70 (Acetyl Lys542) Polyclonal Antibody.)

Rabbit anti-Human Ku-70 Polyclonal Antibody | anti-Ku-70 antibody

Acetyl-Ku-70 (K542) Polyclonal Antibody

Gene Names
Xrcc6; Ku70; 70kDa; G22p1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
Ku-70; Polyclonal Antibody; Acetyl-Ku-70 (K542) Polyclonal Antibody; XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; anti-Ku-70 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (varies by lot)
Sequence Length
12
Applicable Applications for anti-Ku-70 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000, ELISA: 1:5000-1:20000
Immunogen
Synthesized peptide derived from the human Ku-70 around the acetylation site of K542.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Jurkat cells with Ku-70 (Acetyl Lys542) Polyclonal Antibody.)

Western Blot (WB) (Western Blot analysis of Jurkat cells with Ku-70 (Acetyl Lys542) Polyclonal Antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast tissue using Ku-70 (Acetyl Lys542) Polyclonal Antibody at dilution of 1:100.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast tissue using Ku-70 (Acetyl Lys542) Polyclonal Antibody at dilution of 1:100.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human brain tissue using Ku-70 (Acetyl Lys542) Polyclonal Antibody at dilution of 1:100.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human brain tissue using Ku-70 (Acetyl Lys542) Polyclonal Antibody at dilution of 1:100.)
Product Categories/Family for anti-Ku-70 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
Calculated MW: 70
Observed MW: 100, 70
NCBI Official Full Name
Ku 70, partial
NCBI Official Synonym Full Names
X-ray repair complementing defective repair in Chinese hamster cells 6
NCBI Official Symbol
Xrcc6
NCBI Official Synonym Symbols
Ku70; 70kDa; G22p1
NCBI Protein Information
X-ray repair cross-complementing protein 6
UniProt Protein Name
X-ray repair cross-complementing protein 6
UniProt Gene Name
Xrcc6
UniProt Synonym Gene Names
G22p1; Ku70; 5'-dRP/AP lyase Ku70; CTC75; CTCBF; Ku70
UniProt Entry Name
XRCC6_MOUSE

Uniprot Description

Ku70: a mini-chromosome maintenance protein, essential for the initiation of eukaryotic genome replication. Allows DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.

Protein type: RNA-binding; DNA repair, damage; EC 4.2.99.-; EC 3.6.4.-; DNA-binding; Nuclear receptor co-regulator; Helicase

Cellular Component: chromosome; cytoplasm; membrane; nuclear chromosome, telomeric region; nucleolus; nucleoplasm; nucleus; protein complex; transcription factor complex

Molecular Function: 5'-deoxyribose-5-phosphate lyase activity; ATP binding; ATP-dependent DNA helicase activity; catalytic activity; damaged DNA binding; DNA binding; double-stranded DNA binding; double-stranded telomeric DNA binding; helicase activity; hydrolase activity; lyase activity; nucleotide binding; protein binding; protein C-terminus binding; telomeric DNA binding

Biological Process: DNA duplex unwinding; DNA recombination; DNA repair; double-strand break repair; double-strand break repair via nonhomologous end joining; metabolic process; negative regulation of transcription, DNA-dependent; positive regulation of neurogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein heterotetramerization; regulation of smooth muscle cell proliferation; regulation of transcription, DNA-dependent; response to DNA damage stimulus; response to ionizing radiation; telomere maintenance; transcription, DNA-dependent; V(D)J recombination

Research Articles on Ku-70

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Product Notes

The Ku-70 xrcc6 (Catalog #AAA2539187) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Acetyl-Ku-70 (K542) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ku-70 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000, ELISA: 1:5000-1:20000. Researchers should empirically determine the suitability of the Ku-70 xrcc6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ku-70, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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