Rabbit anti-Human KRT75 Polyclonal Antibody | anti-KRT75 antibody

KRT75, NT (KRT75, K6HF, KB18, Keratin, type II cytoskeletal 75, Cytokeratin-75, Keratin-6 hair follicle, Keratin-75, Type II keratin-K6hf, Type-II keratin Kb18) (MaxLight 405)

Cat. Num. AAA6314782

• Gene Names: KRT75; PFB; K6HF; KB18
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: KRT75; Polyclonal Antibody; NT (KRT75; K6HF; KB18; Keratin; type II cytoskeletal 75; Cytokeratin-75; Keratin-6 hair follicle; Keratin-75; Type II keratin-K6hf; Type-II keratin Kb18) (MaxLight 405); Type-II keratin Kb18; anti-KRT75 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

• Applicable Applications for anti-KRT75 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KRT75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-92 amino acids from the N-terminal region of human KRT75.
• Conjugate: MaxLight405
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-KRT75 antibody

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).

Product Categories/Family for anti-KRT75 antibody

Antibodies; Cytokeratin

References

Sperling, L.C., et al. J. Cutan. Pathol. 37(2):243-248(2010). Liu, Z.B., et al. Tumori 95(1):53-62(2009). Nofech-Mozes, S., et al. Int. J. Surg. Pathol. 16(4):399-406(2008). Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006). Roh, C., et al. Physiol. Genomics 19(2):207-217(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 153791158
• NCBI GeneID: 9119
• NCBI Accession #: NP_004684.2
• NCBI GenBank Nucleotide #: NM_004693.2
• UniProt Accession #: O95678; Q9NSA9; B4DQU4
• Molecular Weight: 59,560 Da
• NCBI Official Full Name: keratin, type II cytoskeletal 75
• NCBI Official Synonym Full Names: keratin 75, type II
• NCBI Official Symbol: KRT75
• NCBI Official Synonym Symbols: PFB; K6HF; KB18
• NCBI Protein Information: keratin, type II cytoskeletal 75
• UniProt Protein Name: Keratin, type II cytoskeletal 75
• Protein Family: Keratin
• UniProt Gene Name: KRT75
• UniProt Synonym Gene Names: K6HF; KB18
• UniProt Entry Name: K2C75_HUMAN

NCBI Description

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS). [provided by RefSeq, Oct 2008]