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Western Blot (WB) (KRT73 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KRT73 antibody detected the KRT73 protein (arrow).)

Rabbit anti-Human KRT73 Polyclonal Antibody | anti-KRT73 antibody

KRT73, CT (KRT73, K6IRS3, KB36, KRT6IRS3, Keratin, type II cytoskeletal 73, Cytokeratin-73, Keratin-73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36) (AP)

Gene Names
KRT73; K6IRS3; IRT6IRS3; KRT6IRS3
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
KRT73; Polyclonal Antibody; CT (KRT73; K6IRS3; KB36; KRT6IRS3; Keratin; type II cytoskeletal 73; Cytokeratin-73; Keratin-73; Type II inner root sheath-specific keratin-K6irs3; Type-II keratin Kb36) (AP); Type-II keratin Kb36; anti-KRT73 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-KRT73 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
KRT73 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-530 amino acids from the C-terminal region of human KRT73.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(KRT73 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KRT73 antibody detected the KRT73 protein (arrow).)

Western Blot (WB) (KRT73 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KRT73 antibody detected the KRT73 protein (arrow).)

Immunohistochemistry (IHC)

(KRT73 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded m.heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT73 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (KRT73 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded m.heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT73 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-KRT73 antibody
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.
Product Categories/Family for anti-KRT73 antibody
References
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006). Langbein, L., et al. J. Invest. Dermatol. 120(4):512-522(2003).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,984 Da
NCBI Official Full Name
keratin, type II cytoskeletal 73
NCBI Official Synonym Full Names
keratin 73, type II
NCBI Official Symbol
KRT73
NCBI Official Synonym Symbols
K6IRS3; IRT6IRS3; KRT6IRS3
NCBI Protein Information
keratin, type II cytoskeletal 73
UniProt Protein Name
Keratin, type II cytoskeletal 73
Protein Family
UniProt Gene Name
KRT73
UniProt Synonym Gene Names
K6IRS3; KB36; KRT6IRS3; CK-73; K73
UniProt Entry Name
K2C73_HUMAN

NCBI Description

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

Uniprot Description

K6IRS3: Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: keratin filament; nucleus

Molecular Function: structural molecule activity

Research Articles on KRT73

Similar Products

Product Notes

The KRT73 krt73 (Catalog #AAA6314766) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KRT73, CT (KRT73, K6IRS3, KB36, KRT6IRS3, Keratin, type II cytoskeletal 73, Cytokeratin-73, Keratin-73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KRT73 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:10-50 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KRT73 krt73 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KRT73, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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