Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using KRR1 Polyclonal Antibody at dilution of 1:50(×200))
Rabbit anti-Human, Mouse KRR1 Polyclonal Antibody | anti-KRR1 antibody
KRR1 Polyclonal Antibody
Gene Names
KRR1; HRB2; RIP-1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
KRR1; Polyclonal Antibody; KRR1 Polyclonal Antibody; HIV 1 Rev binding protein 2; HIV-1 Rev-binding protein 2; HRB2; KRR1 small subunit processome component homolog; small subunit (SSU) processome component; homolog (yeast); Rev interacting protein 1; Rev-interacting protein 1; RIP 1; Rip-1; anti-KRR1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.9mg/mL (varies by lot)
Sequence Length
381
Applicable Applications for anti-KRR1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:300
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human KRR1
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using KRR1 Polyclonal Antibody at dilution of 1:50(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using KRR1 Polyclonal Antibody at dilution of 1:50(×200))
Related Product Information for anti-KRR1 antibody
The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU). KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.
Product Categories/Family for anti-KRR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
KRR1 small subunit processome component homolog
NCBI Official Synonym Full Names
KRR1 small subunit processome component homolog
NCBI Official Symbol
KRR1
NCBI Official Synonym Symbols
HRB2; RIP-1
NCBI Protein Information
KRR1 small subunit processome component homolog
UniProt Protein Name
KRR1 small subunit processome component homolog
Protein Family
UniProt Gene Name
KRR1
UniProt Synonym Gene Names
HRB2; Rip-1
UniProt Entry Name
KRR1_HUMAN
Uniprot Description
KRR1: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Belongs to the KRR1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; RNA processing
Chromosomal Location of Human Ortholog: 12q21.2
Cellular Component: small subunit processome; intercellular bridge; membrane; cytoplasm; nucleolus; nucleus
Molecular Function: protein binding
Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Research Articles on KRR1
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Product Notes
The KRR1 krr1 (Catalog #AAA2562638) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KRR1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KRR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:300 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the KRR1 krr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KRR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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