Rabbit KRP6 Polyclonal Antibody | anti-KRP6 antibody

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KRP6 Polyclonal Antibody

• Gene Names: KRP6; ACK1; ARABIDOPSIS CDK INHIBITOR 1; AtKRP6; ICK4; KIP-related protein 6; KIP-RELATED PROTEIN 6
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: KRP6; Polyclonal Antibody; Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) KRP6 Polyclonal Antibody; KRP6 Antibody; Cyclin-dependent kinase inhibitor 6; Cyclin-dependent kinase inhibitor p22ack1; Inhibitor/interactor of CDK protein 4; KIP-related protein 6; KRP6 ACK1 ICK4 At3g19150 MVI11.5; anti-KRP6 antibody

• Host: Rabbit
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-KRP6 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Arabidopsis thaliana KRP6 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 15230293
• NCBI GeneID: 821449
• NCBI Accession #: NP_188546.1
• NCBI GenBank Nucleotide #: NM_112802.4
• UniProt Accession #: Q0WNX9; Q8W2K3; Q9LJL5; A8MRW2
• Molecular Weight: 18,929 Da
• NCBI Official Full Name: KIP-related protein 6
• NCBI Official Symbol: KRP6
• NCBI Official Synonym Symbols: ACK1; ARABIDOPSIS CDK INHIBITOR 1; AtKRP6; ICK4; KIP-related protein 6; KIP-RELATED PROTEIN 6
• NCBI Protein Information: KIP-related protein 6
• UniProt Protein Name: Cyclin-dependent kinase inhibitor 6
• Protein Family: Cyclin-dependent kinase inhibitor
• UniProt Gene Name: KRP6
• UniProt Synonym Gene Names: ACK1; ICK4

NCBI Description

Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type cyclins. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. KRP6 appears to be targeted for degradation by RHF1a and RHF2a to allow mitotic divisions during gametogenesis. In addition, KRP6 transcript levels rise prior to and drop following the meitotic divisions of gametogenesis. Elevated levels of KRP6 negatively affect plant development and fertility.

Uniprot Description

Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity. Regulates cell division which is crucial for plant growth, development and morphogenesis. May inhibit CDK kinases specifically involved in the G1/S phase transition.