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Rabbit anti-Human Kringle Containing Transmembrane Protein 1 (KREMEN1) Polyclonal Antibody | anti-KREMEN1 antibody

APC/CY7-Linked Polyclonal Antibody to Kringle Containing Transmembrane Protein 1 (KREMEN1)

Gene Names
KREMEN1; KRM1; KREMEN
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
Kringle Containing Transmembrane Protein 1 (KREMEN1); Polyclonal Antibody; APC/CY7-Linked Polyclonal Antibody to Kringle Containing Transmembrane Protein 1 (KREMEN1); KRM1; KREMEM1; Dickkopf receptor; Kringle-containing protein marking the eye and the nose; anti-KREMEN1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Concentration
>=100ug/ml (varies by lot)
Applicable Applications for anti-KREMEN1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
KREMEN1 (Lys157~Gly390)
Conjugation
APC-Cy7
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032811

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
50,177 Da
NCBI Official Full Name
Kringle containing transmembrane protein 1
NCBI Official Synonym Full Names
kringle containing transmembrane protein 1
NCBI Official Symbol
KREMEN1
NCBI Official Synonym Symbols
KRM1; KREMEN
NCBI Protein Information
kremen protein 1
UniProt Protein Name
Kremen protein 1
Protein Family
UniProt Gene Name
KREMEN1
UniProt Synonym Gene Names
KREMEN; KRM1

NCBI Description

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

KREMEN1: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 22q12.1

Cellular Component: membrane

Molecular Function: protein binding

Biological Process: cell communication

Research Articles on KREMEN1

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Product Notes

The KREMEN1 kremen1 (Catalog #AAA2066614) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC/CY7-Linked Polyclonal Antibody to Kringle Containing Transmembrane Protein 1 (KREMEN1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Kringle Containing Transmembrane Protein 1 (KREMEN1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the KREMEN1 kremen1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kringle Containing Transmembrane Protein 1 (KREMEN1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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