Rabbit anti-Human KPNA7 Polyclonal Antibody | anti-KPNA7 antibody
KPNA7 Antibody
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
KPNA7; Polyclonal Antibody; KPNA7 Antibody; IMA8_HUMAN; Importin alpha 8; Importin subunit alpha-8; Karyopherin 7; Karyopherin alpha 7 (Importin alpha 8); Karyopherin alpha 7; Karyopherin subunit alpha-7; anti-KPNA7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
KPNA7 Antibody detects endogenous levels of KPNA7.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-KPNA7 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human KPNA7.
Conjugation
Unconjugated
Similarity
Belongs to the importin alpha family.
Subunit Structure
Binds very efficiently to importin subunit beta-1/KPNB1 via the IBB domain; this complex dissociates in the presence of RAN-GTP. Shows a limited binding to the RB1 nuclear localization signal (NLS), but not to the SV40, nor NPM1 NLSs.
Function
Functions in nuclear protein import.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,938 Da
NCBI Official Full Name
importin subunit alpha-8
NCBI Official Synonym Full Names
karyopherin alpha 7 (importin alpha 8)
NCBI Official Symbol
KPNA7
NCBI Protein Information
importin subunit alpha-8; karyopherin 7; karyopherin subunit alpha-7
UniProt Protein Name
Importin subunit alpha-8
UniProt Gene Name
KPNA7
UniProt Entry Name
IMA8_HUMAN
Uniprot Description
KPNA7: Functions in nuclear protein import. Belongs to the importin alpha family.
Protein type: Nuclear import
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component: nucleoplasm; cytosol
Molecular Function: protein transporter activity
Biological Process: protein import into nucleus; cytokine and chemokine mediated signaling pathway
Research Articles on KPNA7
1. Bel1 fragment with residues 215-223, which bears the NLS, interacts with KPNA1, KPNA6, and KPNA7.
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Product Notes
The KPNA7 kpna7 (Catalog #AAA9630570) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KPNA7 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KPNA7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the KPNA7 kpna7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KPNA7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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