Rabbit anti-Human, Mouse KLRC1 Polyclonal Antibody | anti-KLRC1 antibody

KLRC1 (Killer Cell Lectin-like Receptor Subfamily C Member 1, CD159 Antigen-like Family Member A, CD159a, NK Cell Receptor A, NKG2A, NKG2, NKG2-A/B-activating NK Receptor, NKG2-A/NKG2-B Type II Integral Membrane Protein)

Cat. Num. AAA628933

• Gene Names: KLRC1; NKG2A; MGC179368
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified; Purified.
• Synonyms: KLRC1; Polyclonal Antibody; KLRC1 (Killer Cell Lectin-like Receptor Subfamily C Member 1; CD159 Antigen-like Family Member A; CD159a; NK Cell Receptor A; NKG2A; NKG2; NKG2-A/B-activating NK Receptor; NKG2-A/NKG2-B Type II Integral Membrane Protein); Anti -KLRC1 (Killer Cell Lectin-like Receptor Subfamily C Member 1; anti-KLRC1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human KLRC1. Species Crossreactivity: mouse.
• Purity/Purification: Purified; Purified.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL

• Applicable Applications for anti-KLRC1 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.; Dilution: Western Blot: 1:500-1:2000. Band at ~26.3kD detected using KLRC1 transfected 293T lysate.
• Immunogen: Full length human KLRC1 (aa1-233) (Accession #NP_002250.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of KLRC1 expression in human spleen using MBS628933.)

Western Blot (WB)

(Western Blot analysis of KLRC1 expression in mouse testis using MBS628933.)

Western Blot (WB)

(Western Blot analysis of KLRC1 expression in transfected 293T cell line using MBS628933. Lane 1: KLRC1 transfected lysate (26.30kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-KLRC1 antibody

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Product Categories/Family for anti-KLRC1 antibody

Antibodies; Abs to Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 274322975
• NCBI GeneID: 514897
• NCBI Accession #: NP_001162059.1
• NCBI GenBank Nucleotide #: NM_001168587.1
• NCBI Official Full Name: killer cell lectin-like receptor subfamily C, member 1
• NCBI Official Symbol: KLRC1
• NCBI Official Synonym Symbols: NKG2A; MGC179368
• NCBI Protein Information: killer cell lectin-like receptor subfamily C, member 1