Western Blot (WB)
(Western blot analysis of KLRA1 in 293 cell lysate with KLRA1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.)
Rabbit KLRA1 Polyclonal Antibody | anti-KLRA1 antibody
KLRA1 Antibody
Gene Names
KLRAP1; Ly49; KLRA#; KLRA1; LY49L; Ly-49L
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
KLRA1 Antibody is affinity chromatography purified via peptide column.
Synonyms
KLRA1; Polyclonal Antibody; KLRA1 Antibody; Ly49; KLRA#; LY49L; Ly-49L; killer cell lectin-like receptor subfamily A; member 1; anti-KLRA1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
KLRA1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
284
Applicable Applications for anti-KLRA1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
KLRA1 antibody can be used for detection of KLRA1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
KLRA1 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human KLRA1.
Buffer
KLRA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
KLRA1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of KLRA1 in 293 cell lysate with KLRA1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.)
Western Blot (WB)
(Western blot analysis of KLRA1 in 293 cell lysate with KLRA1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of KLRA1 in human spleen tissue with KLRA1 antibody at 2.5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of KLRA1 in human spleen tissue with KLRA1 antibody at 2.5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of KLRA1 in Human Spleen cells with KLRA1 antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of KLRA1 in Human Spleen cells with KLRA1 antibody at 20 μg/mL.)
Related Product Information for anti-KLRA1 antibody
KLRA1 Antibody: KLRA1 (also known and Ly49L) is a member of the LY49 family of receptors Natural killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
killer cell lectin-like receptor subfamily A, member 1, isoform CRA_b
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily A pseudogene 1
NCBI Official Symbol
KLRAP1
NCBI Official Synonym Symbols
Ly49; KLRA#; KLRA1; LY49L; Ly-49L
Protein Family
Research Articles on KLRA1
1. Ly49 family receptors are required for cancer immunosurveillance mediated by natural killer cells.
Similar Products
Product Notes
The KLRA1 (Catalog #AAA151024) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLRA1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KLRA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). KLRA1 antibody can be used for detection of KLRA1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the KLRA1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLRA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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