Rabbit anti-Human KLK10 Polyclonal Antibody | anti-KLK10 antibody
KLK10, NT (KLK10, NES1, PRSSL1, Kallikrein-10, Normal epithelial cell-specific 1, Protease serine-like 1) (APC)
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(KLK10 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KLK10 antibody detected the KLK10 protein (arrow).)
Western Blot (WB)
(Western blot analysis of KLK10 (arrow) using rabbit polyclonal KLK10 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK10 gene.)
NCBI and Uniprot Product Information
NCBI Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Uniprot Description
KLK10: Has a tumor-suppressor role for NES1 in breast and prostate cancer. Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein type: Tumor suppressor; Secreted; Secreted, signal peptide; EC 3.4.21.-; Protease
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: extracellular region
Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis; cell cycle
Research Articles on KLK10
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Product Notes
The KLK10 klk10 (Catalog #AAA6314261) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLK10, NT (KLK10, NES1, PRSSL1, Kallikrein-10, Normal epithelial cell-specific 1, Protease serine-like 1) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLK10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KLK10 klk10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLK10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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