Western Blot (WB)
(Western blot analysis of PLAC3 in HeLa cell lysate with PLAC3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit PLAC3 Polyclonal Antibody | anti-PLAC3 antibody
PLAC3 Antibody
Western Blot (WB)
(Western blot analysis of PLAC3 in HeLa cell lysate with PLAC3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of PLAC3 in HeLa cell lysate with PLAC3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunocytochemistry (ICC)
(Immunocytochemistry of PLAC3 in HeLa cells with PLAC3 antibody at 10 ug/mL.)
Immunocytochemistry (ICC)
(Immunocytochemistry of PLAC3 in HeLa cells with PLAC3 antibody at 10 ug/mL.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Uniprot Description
PAPPA2: Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3. Belongs to the peptidase M43B family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.24.-; Protease; Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 1q25.2
Cellular Component: membrane; extracellular region; intracellular
Molecular Function: metallopeptidase activity; zinc ion binding
Biological Process: cellular protein metabolic process; regulation of cell growth; proteolysis; cell differentiation
Research Articles on PLAC3
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Product Notes
The PLAC3 pappa2 (Catalog #AAA9401933) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLAC3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLAC3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the PLAC3 pappa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLAC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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