Rabbit anti-Human, Mouse KLF5 Polyclonal Antibody | anti-KLF5 antibody

KLF5 Antibody

Cat. Num. AAA7127403

• Gene Names: KLF5; CKLF; IKLF; BTEB2
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Antigen Affinity Purification
• Synonyms: KLF5; Polyclonal Antibody; KLF5 Antibody; Kruppel-like factor 6 (intestinal); anti-KLF5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol

• Applicable Applications for anti-KLF5 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: ELISA: 1:1000-1:5000; WB: 1:500-1:2000
• Immunogen: Synthetic peptide of human KLF5
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

SDS-PAGE

(Gel: 10+12+15%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Human lymphoma tissue, Human ovarian tissue, Human colon cancer tissue, Primary antibody: MBS7127403(KLF5 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds )

Product Categories/Family for anti-KLF5 antibody

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 12644412
• NCBI GeneID: 688
• UniProt Accession #: Q13887; Q9UHP8; L0R3U5; L0R4T9
• Molecular Weight: 457
• NCBI Official Full Name: Krueppel-like factor 5
• NCBI Official Synonym Full Names: Kruppel-like factor 5 (intestinal)
• NCBI Official Symbol: KLF5
• NCBI Official Synonym Symbols: CKLF; IKLF; BTEB2
• NCBI Protein Information: Krueppel-like factor 5; Klf5C isoform; BTE-binding protein 2; GC box binding protein 2; colon kruppel-like factor; colon krueppel-like factor; transcription factor BTEB2; intestinal-enriched kruppel-like factor; intestinal-enriched krueppel-like factor; b
• UniProt Protein Name: Krueppel-like factor 5
• Protein Family: Krueppel-like factor
• UniProt Gene Name: KLF5
• UniProt Synonym Gene Names: BTEB2; CKLF; IKLF; BTE-binding protein 2
• UniProt Entry Name: KLF5_HUMAN

NCBI Description

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

Uniprot Description

KLF5: Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q22.1

Cellular Component: nucleoplasm; Golgi apparatus; intracellular membrane-bound organelle; cytoplasm; plasma membrane

Molecular Function: protein binding; metal ion binding

Biological Process: transcription from RNA polymerase II promoter; microvillus biogenesis; positive regulation of cell proliferation; positive regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; regulation of microvillus biogenesis