Rabbit anti-Mouse KLF13 Polyclonal Antibody | anti-KLF13 antibody

KLF13 (Krueppel-like Factor 13, Basic Transcription Element-binding Protein 3, BTE-binding Protein 3, Novel Sp1-like Zinc Finger Transcription Factor 1, RANTES Factor of Late Activated T-lymphocytes 1, RFLAT-1, Transcription Factor BTEB3, Transcription Fa

Cat. Num. AAA6003935

• Gene Names: KLF13; BTEB3; FKLF2; NSLP1; RFLAT1; RFLAT-1
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: KLF13; Polyclonal Antibody; KLF13 (Krueppel-like Factor 13; Basic Transcription Element-binding Protein 3; BTE-binding Protein 3; Novel Sp1-like Zinc Finger Transcription Factor 1; RANTES Factor of Late Activated T-lymphocytes 1; RFLAT-1; Transcription Factor BTEB3; Transcription Fa; Anti -KLF13 (Krueppel-like Factor 13; anti-KLF13 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse RFLAT-1.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.02% sodium azide.

• Applicable Applications for anti-KLF13 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.; Dilution: Western Blot: 1:500-1:1000
• Immunogen: Synthetic peptide corresponding to aa27-37 [PREGPESRPEG] of RFLAT-1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of RFLAT-1 in transfected COS cells using MBS6003935 at 1:500 dilution.)

Related Product Information for anti-KLF13 antibody

RFLAT-1 is a novel protein belonging to the TFIIIA-like zinc finger protein superfamily and binds to the A site of the RANTES (Regulated upon Activation, Normal T cell Expressed and Secreted) chemokine. RANTES is involved in the generation of inflammatory infiltrate and HIV entry into immune cells.

Product Categories/Family for anti-KLF13 antibody

Antibodies; Abs to Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 37693995
• NCBI GeneID: 51621
• NCBI Accession #: NP_057079.2
• NCBI GenBank Nucleotide #: NM_015995.2
• UniProt Accession #: Q9Y2Y9; Q9Y356
• Molecular Weight: 31,180 Da
• NCBI Official Full Name: Krueppel-like factor 13
• NCBI Official Synonym Full Names: Kruppel-like factor 13
• NCBI Official Symbol: KLF13
• NCBI Official Synonym Symbols: BTEB3; FKLF2; NSLP1; RFLAT1; RFLAT-1
• NCBI Protein Information: Krueppel-like factor 13; BTE-binding protein 3; transcription factor BTEB3; transcription factor NSLP1; Sp1 like zinc finger transcription factor; basic transcription element binding protein 3; basic transcription element-binding protein 3; RANTES factor of late activated T lymphocytes-1; RANTES factor of late activated T-lymphocytes 1; novel Sp1-like zinc finger transcription factor 1
• UniProt Protein Name: Krueppel-like factor 13
• Protein Family: Krueppel-like factor
• UniProt Gene Name: KLF13
• UniProt Synonym Gene Names: BTEB3; NSLP1; BTE-binding protein 3; RFLAT-1
• UniProt Entry Name: KLF13_HUMAN

NCBI Description

KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]

Uniprot Description

KLF13: Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells. Belongs to the Sp1 C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 15q12

Cellular Component: nucleus

Molecular Function: protein binding; DNA binding; metal ion binding

Biological Process: transcription from RNA polymerase II promoter; negative regulation of cell proliferation; negative regulation of erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter

Disease: Chromosome 15q13.3 Deletion Syndrome