Rabbit KLF13 Polyclonal Antibody | anti-KLF13 antibody

KLF13 (Acetyl-K166) Polyclonal Antibody

Cat. Num. AAA3007889

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >96% (by SDS-PAGE).
• Synonyms: KLF13; Polyclonal Antibody; KLF13 (Acetyl-K166) Polyclonal Antibody; Krueppel-like factor 13; Basic transcription element-binding protein 3; BTE-binding protein 3; Novel Sp1-like zinc finger transcription factor 1; RANTES factor of late activated T-lymphocytes 1; RFLAT-1; Transcription factor BTEB3; Transcription factor NSLP1; BTEB3; NSLP1; anti-KLF13 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: KLF13 (Acetyl-K166) polyclonal antibodydetects endogenous levels of KLF13 protein when Acetyl at K166.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >96% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 288

• Applicable Applications for anti-KLF13 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide including acetyl-lysine 166 of KLF13.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of KLF13 (Acetyl-K166) polyclonal antibodyat 1:500 dilutionLane1:Hela whole cell lysate (40ug) Lane2:Jurkat whole cell lysate (40ug) Lane3:NIH-3T3 whole cell lysate (40ug) Lane4:PC12 whole cell lysate (40ug))

Related Product Information for anti-KLF13 antibody

KLF13 belongs to a family of transcription factors thatcontain 3 classical zinc finger DNA-binding domains consisting of azinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines(C2H2 motif). These transcription factors bind to GC-rich sequencesand related GT and CACCC boxes.

NCBI and Uniprot Product Information

• NCBI GI #: 17369913
• UniProt Accession #: Q9Y2Y9
• Molecular Weight: ~ 31kDa
• NCBI Official Full Name: Krueppel-like factor 13
• UniProt Protein Name: Krueppel-like factor 13
• Protein Family: Krueppel-like factor
• UniProt Gene Name: KLF13
• UniProt Synonym Gene Names: BTEB3; NSLP1
• UniProt Entry Name: KLF13_HUMAN

Uniprot Description

KLF13: Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells. Belongs to the Sp1 C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 15q12

Cellular Component: nucleus

Molecular Function: protein binding; DNA binding; metal ion binding

Biological Process: transcription from RNA polymerase II promoter; negative regulation of cell proliferation; negative regulation of erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter

Disease: Chromosome 15q13.3 Deletion Syndrome