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Western Blot (WB) (KLC3 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the KLC3 antibody detected the KLC3 protein (arrow).)

Rabbit KLC3 Polyclonal Antibody | anti-KLC3 antibody

KLC3 Antibody (Center)

Gene Names
KLC3; KLC2; KLCt; KLC2L; KNS2B
Reactivity
Human, mouse (Predicted Reactivity: Bovine)
Applications
Western Blot, ELISA, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
KLC3; Polyclonal Antibody; KLC3 Antibody (Center); Kinesin light chain 3; KLC2-like; kinesin light chain 2; KLC2; KLC2L; anti-KLC3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This KLC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the Central region of human KLC3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
245-274
Sequence Length
518
Applicable Applications for anti-KLC3 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(KLC3 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the KLC3 antibody detected the KLC3 protein (arrow).)

Western Blot (WB) (KLC3 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the KLC3 antibody detected the KLC3 protein (arrow).)

Immunohistochemistry (IHC)

(KLC3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KLC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (KLC3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KLC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(KLC3 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (KLC3 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-KLC3 antibody
KLC3 encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
Product Categories/Family for anti-KLC3 antibody
References
Zhang, Y., et al. Dev. Biol. 275(1):23-33(2004)
Bhullar, B., et al. J. Biol. Chem. 278(18):16159-16168(2003)
Junco, A., et al. Biol. Reprod. 64(5):1320-1330(2001)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55364
NCBI Official Full Name
kinesin light chain 3
NCBI Official Synonym Full Names
kinesin light chain 3
NCBI Official Symbol
KLC3
NCBI Official Synonym Symbols
KLC2; KLCt; KLC2L; KNS2B
NCBI Protein Information
kinesin light chain 3
UniProt Protein Name
Kinesin light chain 3
Protein Family
UniProt Gene Name
KLC3
UniProt Synonym Gene Names
KLC2; KLC2L
UniProt Entry Name
KLC3_HUMAN

NCBI Description

This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]

Uniprot Description

KLC3: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Belongs to the kinesin light chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: ciliary rootlet; microtubule; kinesin complex; neuron projection; cytoplasm

Molecular Function: kinesin binding; microtubule binding; microtubule motor activity

Biological Process: metabolic process; axon cargo transport

Research Articles on KLC3

Similar Products

Product Notes

The KLC3 klc3 (Catalog #AAA9212605) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 245-274. The KLC3 Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's KLC3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the KLC3 klc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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