Western Blot (WB)
(All lanes : Anti-KIST Antibody (L280) at 1:1000 dilutionLane 1: human skeletal muscle lysateLane 2: A-673 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit KIST Polyclonal Antibody | anti-UHMK1 antibody
KIST (KIS) Antibody (C-term)
Western Blot (WB)
(All lanes : Anti-KIST Antibody (L280) at 1:1000 dilutionLane 1: human skeletal muscle lysateLane 2: A-673 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-KIST Antibody (L280) at 1:1000 dilutionLane 1: human skeletal muscle lysateLane 2: A-673 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(The anti-KIST Pab is used in Western blot to detect KIST in K562 cell lysate (Lane 1) and mouse liver tissue lysate (Lane 2).)
Western Blot (WB)
(The anti-KIST Pab is used in Western blot to detect KIST in K562 cell lysate (Lane 1) and mouse liver tissue lysate (Lane 2).)
Background: Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).
NCBI and Uniprot Product Information
NCBI Description
The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Uniprot Description
KIS: a unique kinase that possesses an RNP type RNA-recognition motif (RRM). A proline-directed kinase with a specificity different from the MAP kinases and CDKs. May be involved in trafficking and/or processing of RNA.
Protein type: Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; Other group; Other-Unique family
Chromosomal Location of Human Ortholog: 1q23.3
Cellular Component: axon; dendrite cytoplasm; nucleus
Molecular Function: ATP binding; mRNA binding; protein binding; protein serine/threonine kinase activity; ribonucleoprotein binding; transferase activity
Biological Process: cell cycle arrest; mRNA catabolic process, nonsense-mediated decay; neurite development; peptidyl-serine phosphorylation; positive regulation of translational initiation; protein amino acid autophosphorylation; regulation of alternative nuclear mRNA splicing, via spliceosome; regulation of protein export from nucleus
Research Articles on UHMK1
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Product Notes
The UHMK1 uhmk1 (Catalog #AAA9217134) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KIST (KIS) Antibody (C-term) reacts with Human, Mouse; Predicted Reactivity: Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KIST can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB:~~1:1000. Researchers should empirically determine the suitability of the UHMK1 uhmk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIST, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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