Goat KIF4A Polyclonal Antibody | anti-KIF4A antibody
Goat anti-KIF4A Antibody
Western Blot: An anonymous customer found positive results in WB on Human HeLa cells.
Immunofluorescence: This antibody has been successfully used in IF on HeLa (methanol-fixed, and BSA-blocked) by a customer.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010]
Uniprot Description
KIF4A: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization. Belongs to the kinesin-like protein family. Chromokinesin subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: Xq13.1
Cellular Component: chromosome; cytoplasm; cytosol; kinesin complex; membrane; midbody; nuclear matrix; nucleoplasm; spindle microtubule
Molecular Function: ATP binding; DNA binding; microtubule binding; microtubule motor activity; plus-end-directed microtubule motor activity; protein binding
Biological Process: anterograde axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokinesis after mitosis; metabolic process; microtubule-based movement; organelle organization and biogenesis; retrograde vesicle-mediated transport, Golgi to ER; spindle midzone assembly involved in mitosis
Disease: Mental Retardation, X-linked 100
Research Articles on KIF4A
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Product Notes
The KIF4A kif4a (Catalog #AAA421516) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-KIF4A Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Pig, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's KIF4A can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: An anonymous customer found positive results in WB on Human HeLa cells. Immunofluorescence: This antibody has been successfully used in IF on HeLa (methanol-fixed, and BSA-blocked) by a customer. Researchers should empirically determine the suitability of the KIF4A kif4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SFFSGCSPIE EEAH. It is sometimes possible for the material contained within the vial of "KIF4A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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