Western Blot (WB)
(Western blot analysis of KIF1B expression in Hela (A), SKOV3 (B) whole cell lysates.)
Rabbit anti-Human, Mouse KIF1B Polyclonal Antibody | anti-KIF1B antibody
Anti-KIF1B Antibody
Western Blot (WB)
(Western blot analysis of KIF1B expression in Hela (A), SKOV3 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of KIF1B expression in Hela (A), SKOV3 (B) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of KIF1B staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of KIF1B staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008]
Uniprot Description
KIF1B: a member of the kinesin motor protein family. Motor for anterograde transport of mitochondria. May play a role in synaptic vesicle transport. Has a microtubule plus end-directed motility. Aberrant expression seen in neuroblastoma. Mutated in Charcot-Marie-Tooth disease.
Protein type: Motor; Microtubule-binding
Chromosomal Location of Human Ortholog: 1p36.2
Cellular Component: cytoplasmic vesicle; cytoplasmic vesicle membrane; kinesin complex; microtubule; microtubule associated complex; mitochondrion; neuron projection
Molecular Function: ATP binding; ATPase activity; kinesin binding; microtubule binding; microtubule motor activity; protein binding
Biological Process: anterograde axon cargo transport; apoptosis; cytoskeleton-dependent intracellular transport; metabolic process; microtubule-based movement; mitochondrion transport along microtubule; nerve-nerve synaptic transmission; neuromuscular synaptic transmission
Disease: Charcot-marie-tooth Disease, Axonal, Type 2a1; Neuroblastoma, Susceptibility To; Pheochromocytoma
Research Articles on KIF1B
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Product Notes
The KIF1B kif1b (Catalog #AAA8245342) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-KIF1B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KIF1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000; IHC: 1/50 - 1/200. Researchers should empirically determine the suitability of the KIF1B kif1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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