Rabbit anti-Human Kidney Injury Molecule 1 (Kim1) Polyclonal Antibody | anti-Kim1 antibody

HRP-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

Cat. Num. AAA2115692

• Gene Names: HAVCR1; TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
• Purity: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Synonyms: Kidney Injury Molecule 1 (Kim1); Polyclonal Antibody; HRP-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1); HAVCR1; TIM1; TIMD1; HAVCR; Hepatitis A Virus Cellular Receptor 1; T Cell Immunoglobulin And Mucin Domain-Containing Protein 1; T-cell immunoglobulin mucin receptor 1; anti-Kim1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody is a rabbit polyclonal antibody raised against Kim1. It has been selected for its ability to recognize Kim1 in immunohistochemical staining and western blotting.
• Purity/Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Form/Format: Liquid; 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
• Concentration: 500ug/ml (varies by lot)
• Sequence: Ser21~Thr293

• Applicable Applications for anti-Kim1 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
• Immunogen Sequence: Ser21~Thr293
• Cross Reactivity: Human
• Conjugation: HRP
• Preparation and Storage: Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.; Avoid repeated freeze/thaw cycles.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Product Categories/Family for anti-Kim1 antibody

Tumor Immunity; Infection Immunity; Kidney Biomarker

NCBI and Uniprot Product Information

• NCBI GI #: 73919877
• NCBI GeneID: 26762
• UniProt Accession #: Q96D42; O43656
• Molecular Weight: 364
• NCBI Official Full Name: Hepatitis A virus cellular receptor 1
• NCBI Official Synonym Full Names: hepatitis A virus cellular receptor 1
• NCBI Official Symbol: HAVCR1
• NCBI Official Synonym Symbols: TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1
• NCBI Protein Information: hepatitis A virus cellular receptor 1; kidney injury molecule 1; T-cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin mucin family member 1; T cell immunoglobin domain and mucin domain protein 1
• UniProt Protein Name: Hepatitis A virus cellular receptor 1
• UniProt Gene Name: HAVCR1
• UniProt Synonym Gene Names: KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1
• UniProt Entry Name: HAVR1_HUMAN

NCBI Description

The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

Uniprot Description

TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: integral to membrane

Molecular Function: viral receptor activity

Biological Process: entry of virus into host cell

Disease: Ige Responsiveness, Atopic