Rabbit anti-Human Ki-67 Protein (Ki67P) Polyclonal Antibody | anti-Ki67P antibody

Botin-Linked Polyclonal Antibody to Ki-67 Protein (Ki67P)

Cat. Num. AAA2109379

• Gene Names: MKI67; KIA; MIB-; MIB-1; PPP1R105
• Reactivity: Human
• Applications: Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
• Purity: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Synonyms: Ki-67 Protein (Ki67P); Polyclonal Antibody; Botin-Linked Polyclonal Antibody to Ki-67 Protein (Ki67P); MKI67; KIA; Ki-67; Antigen Identified By Monoclonal Antibody Ki-67; anti-Ki67P antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody is a Rabbit polyclonal antibody raised against Ki67P. It has been selected for its ability to recognize Ki67P in immunohistochemical staining and western blotting.
• Purity/Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography
• Form/Format: Liquid
• Concentration: 500ug/ml (varies by lot)
• Sequence: Ki67P (Gly3088~Lys3235) linked with LEHHHHHH
• Sequence Length: 2896

• Applicable Applications for anti-Ki67P antibody: Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Frozen/Paraffin, ELISA (EIA)
• Conjugation: Biotin
• Cross Reactivity: Human, Mouse
• Preparation and Storage: Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.; Avoid repeated freeze/thaw cycles.; ; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

NCBI and Uniprot Product Information

• NCBI GI #: 225543215
• NCBI GeneID: 4288
• NCBI Accession #: NP_001139438.1
• NCBI GenBank Nucleotide #: NM_001145966.1
• UniProt Accession #: P46013
• NCBI Official Full Name: proliferation marker protein Ki-67 isoform 2
• NCBI Official Synonym Full Names: marker of proliferation Ki-67
• NCBI Official Symbol: MKI67
• NCBI Official Synonym Symbols: KIA; MIB-; MIB-1; PPP1R105
• NCBI Protein Information: proliferation marker protein Ki-67
• UniProt Protein Name: Antigen KI-67
• UniProt Gene Name: MKI67
• UniProt Entry Name: KI67_HUMAN

NCBI Description

This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]

Uniprot Description

KI-67: a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers.

Protein type: Nucleolus; Cell cycle regulation

Chromosomal Location of Human Ortholog: 10q26.2

Cellular Component: membrane; cytoplasm; nucleolus; condensed chromosome; nucleus; chromosome, pericentric region

Molecular Function: protein C-terminus binding; protein binding; ATP binding

Biological Process: cell proliferation; meiosis