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SDS-PAGE

Antigen KI-67 Recombinant Protein | MKI67 recombinant protein

Recombinant Human Antigen KI-67, partial

Gene Names
MKI67; KIA; MIB-; MIB-1; PPP1R105
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Antigen KI-67; Recombinant Human Antigen KI-67; partial; Homo sapiens (Human); MKI67 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2720-3256. Partial
Sequence
TKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIRTRSHRDSEDI
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

SDS-PAGE
Related Product Information for MKI67 recombinant protein
Thought to be required for maintaining cell proliferation.
Product Categories/Family for MKI67 recombinant protein
References
"The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins." Schlueter C., Duchrow M., Wohlenberg C., Becker M.H.G., Key G., Flad H.-D., Gerdes J. J. Cell Biol. 123:513-522(1993)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75.1 kDa
NCBI Official Full Name
antigen KI-67 isoform 2
NCBI Official Synonym Full Names
marker of proliferation Ki-67
NCBI Official Symbol
MKI67
NCBI Official Synonym Symbols
KIA; MIB-; MIB-1; PPP1R105
NCBI Protein Information
antigen KI-67
UniProt Protein Name
Antigen KI-67
UniProt Gene Name
MKI67
UniProt Entry Name
KI67_HUMAN

NCBI Description

This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]

Uniprot Description

KI-67: a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers.

Protein type: Cell cycle regulation; Nucleolus

Chromosomal Location of Human Ortholog: 10q26.2

Cellular Component: chromosome, pericentric region; condensed chromosome; cytoplasm; membrane; nucleolus; nucleus

Molecular Function: ATP binding; protein binding; protein C-terminus binding

Biological Process: cell proliferation; DNA metabolic process; hyaluronan metabolic process; meiosis; organ regeneration; response to organic cyclic substance

Research Articles on MKI67

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Product Notes

The MKI67 mki67 (Catalog #AAA969564) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2720-3256. Partial. The amino acid sequence is listed below: TKRHLRTRVQ KVQVKEEPSA VKFTQTSGET TDADKEPAGE DKGIKALKES AKQTPAPAAS VTGSRRRPRA PRESAQAIED LAGFKDPAAG HTEESMTDDK TTKIPCKSSP ELEDTATSSK RRPRTRAQKV EVKEELLAVG KLTQTSGETT HTDKEPVGEG KGTKAFKQPA KRKLDAEDVI GSRRQPRAPK EKAQPLEDLA SFQELSQTPG HTEELANGAA DSFTSAPKQT PDSGKPLKIS RRVLRAPKVE PVGDVVSTRD PVKSQSKSNT SLPPLPFKRG GGKDGSVTGT KRLRCMPAPE EIVEELPASK KQRVAPRARG KSSEPVVIMK RSLRTSAKRI EPAEELNSND MKTNKEEHKL QDSVPENKGI SLRSRRQNKT EAEQQITEVF VLAERIEINR NEKKPMKTSP EMDIQNPDDG ARKPIPRDKV TENKRCLRSA RQNESSQPKV AEESGGQKSA KVLMQNQKGK GEAGNSDSMC LRSRKTKSQP AASTLESKSV QRVTRSVKRC AENPKKAEDN VCVKKIRTRS HRDSEDI . It is sometimes possible for the material contained within the vial of "Antigen KI-67, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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