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Western Blot (WB)
(Western Blot (WB) analysis of KHSRP Rabbit mAb at 1:1000 dilutionLane1:293 whole cell lysateLane2:The brain tissue lysate of MouseLane3:The brain tissue lysate of Rat)
Rabbit KHSRP Polyclonal Antibody | anti-KHSRP antibody
KHSRP Polyclonal Antibody
Gene Names
KHSRP; p75; FBP2; KSRP; FUBP2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation, Flow Cytometry, Functional Assay
Purity
Protein A affinity purified.
Synonyms
KHSRP; Polyclonal Antibody; KHSRP Polyclonal Antibody; Far upstream element-binding protein 2; FUSE-binding protein 2; KH type-splicing regulatory protein; KSRP; p75; FUBP2; anti-KHSRP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody detects endogenous levels of KHSRP and does not cross-react with related proteins.
Purity/Purification
Protein A affinity purified.
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
711
Applicable Applications for anti-KHSRP antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:500-1:2000
ICC: 1:50-1:200
IHC: 1:50-1:200
IP: 1:10-1:50
ICC: 1:50-1:200
IHC: 1:50-1:200
IP: 1:10-1:50
Immunogen
Recombinant protein within human KHSRP aa 1-150.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of KHSRP Rabbit mAb at 1:1000 dilutionLane1:293 whole cell lysateLane2:The brain tissue lysate of MouseLane3:The brain tissue lysate of Rat)
Western Blot (WB)
(Western Blot (WB) analysis of KHSRP Rabbit mAb at 1:1000 dilutionLane1:293 whole cell lysateLane2:The brain tissue lysate of MouseLane3:The brain tissue lysate of Rat)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-KHSRP antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-KHSRP antibody. Counter stained with hematoxylin.)
Immunocytochemistry (ICC)
(ICC staining KHSRP in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Immunocytochemistry (ICC)
(ICC staining KHSRP in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Immunohistochemistry (IHC)
(Immunohistochemical analysisparaffin-embedded rat testis tissueanti-KHSRP antibody. Counter stainedhematoxylin. )
Immunohistochemistry (IHC)
(Immunohistochemical analysisparaffin-embedded rat testis tissueanti-KHSRP antibody. Counter stainedhematoxylin. )
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-KHSRP antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-KHSRP antibody. Counter stained with hematoxylin.)
Related Product Information for anti-KHSRP antibody
Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 73kDa
NCBI Official Full Name
Far upstream element-binding protein 2
NCBI Official Synonym Full Names
KH-type splicing regulatory protein
NCBI Official Symbol
KHSRP
NCBI Official Synonym Symbols
p75; FBP2; KSRP; FUBP2
NCBI Protein Information
far upstream element-binding protein 2
UniProt Protein Name
Far upstream element-binding protein 2
Protein Family
UniProt Gene Name
KHSRP
UniProt Synonym Gene Names
FUBP2; FUSE-binding protein 2; KSRP
UniProt Entry Name
FUBP2_HUMAN
NCBI Description
The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010]
Research Articles on KHSRP
Similar Products
Product Notes
The KHSRP khsrp (Catalog #AAA3014177) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KHSRP Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KHSRP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS). WB: 1:500-1:2000 ICC: 1:50-1:200 IHC: 1:50-1:200 IP: 1:10-1:50. Researchers should empirically determine the suitability of the KHSRP khsrp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KHSRP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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