Rabbit anti-Human KHDRBS2 Polyclonal Antibody | anti-KHDRBS2 antibody

KHDRBS2 Antibody

Cat. Num. AAA7003696

• Gene Names: KHDRBS2; SLM1; SLM-1
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >95%,Protein G purified
• Synonyms: KHDRBS2; Polyclonal Antibody; KHDRBS2 Antibody; KH domain-containing; RNA-binding; signal transduction-associated protein 2; Sam68-like mammalian protein 1; SLM-1; hSLM-1; SLM1; anti-KHDRBS2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 349

• Applicable Applications for anti-KHDRBS2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Recombinant human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9473 / sc-28838
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western blotAll lanes: KHDRBS2 antibody at 7ug/mlLane 1: K562 whole cell lysateLane 2: Hela whole cell lysateLane 3: A431 whole cell lysateLane 4: Jurkat whole cell lysateLane 5: NIH/3T3 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 39 kDaObserved band size: 39 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7003696 at dilution of 1:100)

Related Product Information for anti-KHDRBS2 antibody

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.

NCBI and Uniprot Product Information

• NCBI GI #: 189217895
• NCBI GeneID: 202559
• NCBI Accession #: NP_689901.2
• NCBI GenBank Nucleotide #: NM_152688.3
• UniProt Accession #: Q5VWX1; Q8N4I4; Q8TCZ4; A8K7M8
• Molecular Weight: 38,927 Da
• NCBI Official Full Name: KH domain-containing, RNA-binding, signal transduction-associated protein 2
• NCBI Official Synonym Full Names: KH domain containing, RNA binding, signal transduction associated 2
• NCBI Official Symbol: KHDRBS2
• NCBI Official Synonym Symbols: SLM1; SLM-1
• NCBI Protein Information: KH domain-containing, RNA-binding, signal transduction-associated protein 2
• UniProt Protein Name: KH domain-containing, RNA-binding, signal transduction-associated protein 2
• Protein Family: KH domain-containing, RNA-binding, signal transduction-associated protein
• UniProt Gene Name: KHDRBS2
• UniProt Synonym Gene Names: SLM1; SLM-1; hSLM-1
• UniProt Entry Name: KHDR2_HUMAN

Uniprot Description

KHDRBS2: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Belongs to the KHDRBS family.

Chromosomal Location of Human Ortholog: 6q11.1

Cellular Component: nucleus

Molecular Function: poly(A) binding; poly(U) binding; protein binding; protein heterodimerization activity; SH2 domain binding; SH3 domain binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent