Rabbit kelch-like 3 Polyclonal Antibody | anti-KLHL3 antibody
Rabbit anti-human kelch-like 3 (Drosophila) polyclonal Antibody
Reactivity
Human,Mouse,Rat?Other species are not tested. Please decide the specificity by homology.
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
kelch-like 3; Polyclonal Antibody; Rabbit anti-human kelch-like 3 (Drosophila) polyclonal Antibody; kelch-like 3 (Drosophila); KLHL3; FLJ40871; KIAA1129; MGC44594; anti-KLHL3 antibody
Host
Rabbit
Reactivity
Human,Mouse,Rat?Other species are not tested. Please decide the specificity by homology.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
587
Applicable Applications for anti-KLHL3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: Use at an assay dependent dilution.
WB: 1:200-1:2000
IP:1:200-1:2000
IHC: 1:50-1:200(Recommender dilutions)
Positive WB detected in: HepG2 cells, HL-60 cells, human liver tissue, Jurkat cells, mouse liver tissue, mouse thymus tissue, rat liver tissue
Positive IP detected in : HepG2 cells
Positive IHC detected in: Human liver tissue,human tonsillitis tissue
WB: 1:200-1:2000
IP:1:200-1:2000
IHC: 1:50-1:200(Recommender dilutions)
Positive WB detected in: HepG2 cells, HL-60 cells, human liver tissue, Jurkat cells, mouse liver tissue, mouse thymus tissue, rat liver tissue
Positive IP detected in : HepG2 cells
Positive IHC detected in: Human liver tissue,human tonsillitis tissue
Immunogen
Human KLHL3
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133714
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-KLHL3 antibody
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
kelch-like protein 3
NCBI Official Symbol
KLHL3
NCBI Protein Information
kelch-like protein 3; kelch-like 3
UniProt Protein Name
Kelch-like protein 3
Protein Family
UniProt Gene Name
KLHL3
UniProt Entry Name
KLHL3_PONAB
Uniprot Description
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation ().
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Product Notes
The KLHL3 klhl3 (Catalog #AAA711933) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human kelch-like 3 (Drosophila) polyclonal Antibody reacts with Human,Mouse,Rat?Other species are not tested. Please decide the specificity by homology. and may cross-react with other species as described in the data sheet. AAA Biotech's kelch-like 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: Use at an assay dependent dilution. WB: 1:200-1:2000 IP:1:200-1:2000 IHC: 1:50-1:200(Recommender dilutions) Positive WB detected in: HepG2 cells, HL-60 cells, human liver tissue, Jurkat cells, mouse liver tissue, mouse thymus tissue, rat liver tissue Positive IP detected in : HepG2 cells Positive IHC detected in: Human liver tissue,human tonsillitis tissue. Researchers should empirically determine the suitability of the KLHL3 klhl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "kelch-like 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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