Testing Data
Rabbit KDSR Polyclonal Antibody | anti-KDSR antibody
KDSR Antibody
WB: 1:200-1:1000
Testing Data
Testing Data
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008]
Uniprot Description
FVT1: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein type: Oncoprotein; Membrane protein, integral; EC 1.1.1.102; Lipid Metabolism - sphingolipid; Membrane protein, multi-pass; Oxidoreductase
Chromosomal Location of Human Ortholog: 18q21.3
Cellular Component: extracellular space; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: 3-dehydrosphinganine reductase activity
Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; 3-keto-sphinganine metabolic process
Research Articles on KDSR
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Product Notes
The KDSR kdsr (Catalog #AAA9403986) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KDSR Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KDSR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20000-1:80000 WB: 1:200-1:1000. Researchers should empirically determine the suitability of the KDSR kdsr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDSR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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