Rabbit anti-Human KATL1 Polyclonal Antibody | anti-KATL1 antibody

KATL1, NT (KATNAL1, Katanin p60 ATPase-containing subunit A-like 1, p60 katanin-like 1) (MaxLight 405)

Cat. Num. AAA6312109

• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: KATL1; Polyclonal Antibody; NT (KATNAL1; Katanin p60 ATPase-containing subunit A-like 1; p60 katanin-like 1) (MaxLight 405); KATNAL1; p60 katanin-like 1; anti-KATL1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

• Applicable Applications for anti-KATL1 antibody: Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: FC/FACS: 1:10-50; FLISA: 1:1,000; IHC: 1:50-100; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: KATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the N-terminal region of human KATL1.
• Conjugate: MaxLight405
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-KATL1 antibody

MaxLight405 is a new Violet photostable dye conjugate comparable to Alexa Fluor 405, PacificBlue, Brilliant Violet 421 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (400nm); Emission (423nm); Extinction Coefficient 32,000.

Product Categories/Family for anti-KATL1 antibody

Antibodies; Enzymes; ATPase

References

Dunham, A., et al. Nature 428(6982):522-528(2004). Millar, J.K., et al. Biochem. Biophys. Res. Commun. 311(4):1019-1025(2003). Robertson, N.G., et al. Genomics 23(1):42-50(1994).

NCBI and Uniprot Product Information

• NCBI GI #: 14149767
• NCBI GeneID: 84056
• NCBI Accession #: NP_115492.1; NP_001014402.1
• NCBI GenBank Nucleotide #: NM_032116.4
• UniProt Accession #: Q9BW62; A8K5X4
• Molecular Weight: 55,392 Da
• NCBI Official Full Name: katanin p60 ATPase-containing subunit A-like 1
• NCBI Official Synonym Full Names: katanin catalytic subunit A1 like 1
• NCBI Official Symbol: KATNAL1
• NCBI Protein Information: katanin p60 ATPase-containing subunit A-like 1
• UniProt Protein Name: Katanin p60 ATPase-containing subunit A-like 1
• UniProt Gene Name: KATNAL1
• UniProt Synonym Gene Names: Katanin p60 subunit A-like 1
• UniProt Entry Name: KATL1_HUMAN

Uniprot Description

KATNAL1: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays. Belongs to the AAA ATPase family.

Protein type: EC 3.6.4.3; Hydrolase

Chromosomal Location of Human Ortholog: 13q12.3

Cellular Component: microtubule; cytoplasm; nucleus

Molecular Function: microtubule binding; microtubule-severing ATPase activity; ATP binding

Biological Process: metabolic process; microtubule severing; spermatogenesis; cytoplasmic microtubule organization and biogenesis