Western Blot (WB)
(Host: RabbitTarget Name: KALRNSample Tissue: Human HCT116 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Human KALRN Polyclonal Antibody | anti-KALRN antibody
KALRN Antibody - middle region
Gene Names
KALRN; DUO; CHD5; DUET; TRAD; CHDS5; HAPIP; ARHGEF24
Reactivity
Human
Applications
Western Blot
Purity
Affinity purified
Synonyms
KALRN; Polyclonal Antibody; KALRN Antibody - middle region; anti-KALRN antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: GRKSFDLGSPKPGDETTPQGDSADEKSKKGWGEDEPDEESHTPLPPPMKI
Sequence Length
738
Applicable Applications for anti-KALRN antibody
Western Blot (WB)
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human KALRN
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Host: RabbitTarget Name: KALRNSample Tissue: Human HCT116 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: KALRNSample Tissue: Human HCT116 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Related Product Information for anti-KALRN antibody
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described.
Product Categories/Family for anti-KALRN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
81 kDa
NCBI Official Full Name
kalirin isoform 1
NCBI Official Synonym Full Names
kalirin RhoGEF kinase
NCBI Official Symbol
KALRN
NCBI Official Synonym Symbols
DUO; CHD5; DUET; TRAD; CHDS5; HAPIP; ARHGEF24
NCBI Protein Information
kalirin
UniProt Protein Name
Kalirin
Protein Family
UniProt Gene Name
KALRN
NCBI Description
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]
Uniprot Description
Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.
Research Articles on KALRN
Similar Products
Product Notes
The KALRN kalrn (Catalog #AAA3221770) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KALRN Antibody - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KALRN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the KALRN kalrn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GRKSFDLGSP KPGDETTPQG DSADEKSKKG WGEDEPDEES HTPLPPPMKI. It is sometimes possible for the material contained within the vial of "KALRN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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