Rabbit JNK1+JNK2+JNK3 Polyclonal Antibody | anti-JNK1+JNK2+JNK3 antibody

JNK1+JNK2+JNK3 Polyclonal Antibody

Cat. Num. AAA3013902

• Gene Names: Mapk10; JNK3; Serk2; JNK3B1; JNK3B2; p493F12; p54bSAPK; SAPK(beta); C230008H04Rik
• Reactivity: Human, Mouse, Rat; Predicted: Dog, Pig, Cow
• Applications: Western Blot, Immunohistochemistry
• Purity: affinity purified by Protein A
• Synonyms: JNK1+JNK2+JNK3; Polyclonal Antibody; JNK1+JNK2+JNK3 Polyclonal Antibody; JNK1 + JNK2 + JNK3; JNK1/2/3; JNK1+2+3; MAPK10; c Jun N terminal kinase 1; c Jun N terminal kinase 2; c Jun N terminal kinase 3; JNK; JNK1; JNK2; JNK2ALPHA; JNK2BETA; JNK3; MAPK8; MAPK9; Mitogen activated protein kinase 10; Mitogen activated protein kinase 8; Mitogen activated protein kinase 9; SAPK(beta); Stress activated protein kinase JNK1; Stress activated protein kinase JNK2; Stress activated protein kinase JNK3; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; p54aSAPK; anti-JNK1+JNK2+JNK3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat; Predicted: Dog, Pig, Cow
• Clonality: Polyclonal
• Specificity: JNK1+JNK2+JNK3 Polyclonal Antibody detects endogenous levels of JNK1+JNK2+JNK3 protein.
• Purity/Purification: affinity purified by Protein A
• Form/Format: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Applicable Applications for anti-JNK1+JNK2+JNK3 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:500-2000; IHC-P: 1:100-500
• Immunogen: KLH conjugated synthetic peptide derived from human JNK1/2/3:151-250/384
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

Testing Data

Immunohistochemistry (IHC)

(Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (JNK1+JNK2+JNK3) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C,)

Related Product Information for anti-JNK1+JNK2+JNK3 antibody

JNK1(MAPK8) is a member of the MAP kinase family. JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7.JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.JNK3 is a neuron-specific form of c-Jun N-terminal kinases. Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis.The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity.

NCBI and Uniprot Product Information

• NCBI GI #: 568935657
• NCBI GeneID: 26414
• NCBI Accession #: XP_006535014.1
• NCBI GenBank Nucleotide #: XM_006534951.1
• UniProt Accession #: Q61831; Q9R0U6
• Molecular Weight: 52,532 Da
• NCBI Official Full Name: mitogen-activated protein kinase 10 isoform X9
• NCBI Official Synonym Full Names: mitogen-activated protein kinase 10
• NCBI Official Symbol: Mapk10
• NCBI Official Synonym Symbols: JNK3; Serk2; JNK3B1; JNK3B2; p493F12; p54bSAPK; SAPK(beta); C230008H04Rik
• NCBI Protein Information: mitogen-activated protein kinase 10; MAPK 10; MAP kinase 10; SAPK/Erk/kinase 2; MAP kinase p49 3F12; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; c-Jun N-terminal kinase 3; mitogen activated protein kinase 10; stress-activated protein kinase JNK3
• UniProt Protein Name: Mitogen-activated protein kinase 10
• UniProt Gene Name: Mapk10
• UniProt Synonym Gene Names: Jnk3; Prkm10; Serk2; MAP kinase 10; MAPK 10
• UniProt Entry Name: MK10_MOUSE