Rabbit JMJD7 Polyclonal Antibody | anti-JMJD7 antibody

JMJD7 Antibody

Cat. Num. AAA151581

• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: JMJD7 Antibody is affinity chromatography purified via peptide column.
• Synonyms: JMJD7; Polyclonal Antibody; JMJD7 Antibody; JmjC domain-containing protein 7; Jumonji domain-containing protein 7; jumonji domain containing 7; anti-JMJD7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: JMJD7 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 316

• Applicable Applications for anti-JMJD7 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: JMJD7 antibody can be used for detection of JMJD7 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
• Conjugate: Unconjugated
• Immunogen: JMJD7 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human JMJD7.
• Buffer: JMJD7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: JMJD7 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of JMJD7 in 3T3 cell lysate with JMJD7 antibody at 1 μg/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of JMJD7 in rat liver tissue with JMJD7 antibody at 2.5 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of JMJD7 in rat liver tissue with JMJD7 antibody at 20 μg/mL.)

Related Product Information for anti-JMJD7 antibody

JMJD7 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the function of JMJD7 has not been identified. JMJD7 was initially thought to be a novel splice form of the phospholipase PLA2G4B which is located downstream of JMJD7 as most tissues express a read-through transcript of the two genes.

NCBI and Uniprot Product Information

• NCBI GI #: 205783894
• NCBI GeneID: 100137047
• UniProt Accession #: P0C870; O95712; Q59GF9; Q8TB10; Q9UKV7; A5D6V5
• Molecular Weight: 35,932 Da
• NCBI Official Full Name: JmjC domain-containing protein 7
• NCBI Official Synonym Full Names: jumonji domain containing 7
• NCBI Official Symbol: JMJD7
• NCBI Protein Information: jmjC domain-containing protein 7; jumonji domain-containing protein 7
• UniProt Protein Name: JmjC domain-containing protein 7
• Protein Family: JmjC domain-containing protein
• UniProt Gene Name: JMJD7
• UniProt Entry Name: JMJD7_HUMAN

NCBI Description

This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [provided by RefSeq, Jul 2008]

Uniprot Description

JMJD7: a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [RefSeq, Jul 2008]

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q15.1