Rabbit anti-Human JMJD6 Polyclonal Antibody | anti-JMJD6 antibody

JMJD6, CT (JMJD6, KIAA0585, PTDSR, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Histone arginine demethylase JMJD6, JmjC domain-containing protein 6, Jumonji domain-containing protein 6, Lysyl-hydroxylase JMJD6, Peptide-lysine 5-dioxygen

Cat. Num. AAA6311755

• Gene Names: JMJD6; PSR; PTDSR; PTDSR1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: JMJD6; Polyclonal Antibody; CT (JMJD6; KIAA0585; PTDSR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygen; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; anti-JMJD6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-JMJD6 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: JMJD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human JMJD6.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(JMJD6 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the JMJD6 antibody detected the JMJD6 protein (arrow).)

Related Product Information for anti-JMJD6 antibody

This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Product Categories/Family for anti-JMJD6 antibody

Antibodies; Enzymes; Demethylase

References

Hong, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(33):14568-14572(2010). Mantri, M., et al. J. Mol. Biol. 401(2):211-222(2010). Zakharova, L., et al. J. Cell. Physiol. 221(1):84-91(2009). Webby, C.J., et al. Science 325(5936):90-93(2009). Klose, R.J., et al. Nat. Rev. Genet. 7(9):715-727(2006).

NCBI and Uniprot Product Information

• NCBI GI #: 125988389
• NCBI GeneID: 23210
• NCBI Accession #: NP_055982.2; NP_001074930.1
• NCBI GenBank Nucleotide #: NM_015167.2
• UniProt Accession #: Q6NYC1; Q86VY0; Q8IUM5; Q9Y4E2; B3KMN8; B4DGX1
• Molecular Weight: 47,626 Da
• NCBI Official Full Name: bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform 2
• NCBI Official Synonym Full Names: jumonji domain containing 6
• NCBI Official Symbol: JMJD6
• NCBI Official Synonym Symbols: PSR; PTDSR; PTDSR1
• NCBI Protein Information: bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; phosphatidylserine receptor; jmjC domain-containing protein 6; histone arginine demethylase JMJD6; peptide-lysine 5-dioxygenase JMJD6; jumonji domain-containing protein 6
• UniProt Protein Name: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
• Protein Family: Bifunctional arginine demethylase and lysyl-hydroxylase
• UniProt Gene Name: JMJD6
• UniProt Synonym Gene Names: KIAA0585; PTDSR; Protein PTDSR
• UniProt Entry Name: JMJD6_HUMAN

NCBI Description

This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]