Western Blot
Rabbit anti-Human JMJD1C Polyclonal Antibody | anti-JMJD1C antibody
JMJD1C Antibody
Gene Names
JMJD1C; TRIP8
Reactivity
Human
Applications
Western Blot
Purity
Affinity purified
Synonyms
JMJD1C; Polyclonal Antibody; JMJD1C Antibody; JmjC domain-containing histone demethylation protein 2C; jumonji domain-containing protein 1C; thyroid receptor-interacting protein 8; TRIP-8; TRIP8; JHDM2C; FLJ14374; RP11-10C13.2; DKFZp761F0118; KIAA1380; anti-JMJD1C antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
Supplied in PBS pH 7.2, 0.01% BSA, 0.03% ProClin® and 50% glycerol.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
2358
Applicable Applications for anti-JMJD1C antibody
Western Blot (WB)
Application Notes
Western blotting (1 - 4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects JMJ1DC of human origin. Reactivity to other species has not been tested.
Immunogen
Synthetic peptide surrounding amino acid 1003 of human JMJD1C
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
Store at -20°C. For long term storage, aliquot and freeze at-70°C. Avoid repeated freeze/defrost cycles
Western Blot
Western Blot
Related Product Information for anti-JMJD1C antibody
Background: JMJD1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1C has been identified as a nuclear-receptor coactivator and is a candidate gene for autism.
Product Categories/Family for anti-JMJD1C antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
probable JmjC domain-containing histone demethylation protein 2C isoform c
NCBI Official Synonym Full Names
jumonji domain containing 1C
NCBI Official Symbol
JMJD1C
NCBI Official Synonym Symbols
TRIP8
NCBI Protein Information
probable JmjC domain-containing histone demethylation protein 2C
UniProt Protein Name
Probable JmjC domain-containing histone demethylation protein 2C
UniProt Gene Name
JMJD1C
UniProt Synonym Gene Names
JHDM2C; KIAA1380; TRIP8; TR-interacting protein 8; TRIP-8
UniProt Entry Name
JHD2C_HUMAN
Uniprot Description
TRIP8: Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes. Belongs to the JHDM2 histone demethylase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Demethylase; Oxidoreductase; EC 1.14.11.-; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 10q21.3
Cellular Component: nucleoplasm; intracellular
Molecular Function: protein binding; dioxygenase activity; metal ion binding; thyroid hormone receptor binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; chromatin modification; blood coagulation
Research Articles on JMJD1C
Similar Products
Product Notes
The JMJD1C jmjd1c (Catalog #AAA840834) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JMJD1C Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's JMJD1C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (1 - 4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects JMJ1DC of human origin. Reactivity to other species has not been tested. Researchers should empirically determine the suitability of the JMJD1C jmjd1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JMJD1C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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