Rabbit anti-Human DOC2B Polyclonal Antibody | anti-DOC2B antibody

DOC2B Antibody

Cat. Num. AAA9430024

• Gene Names: DOC2B; DOC2BL
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: DOC2B; Polyclonal Antibody; DOC2B Antibody; DOC2BL; anti-DOC2B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total DOC2B protein.
• Purity/Purification: Antigen affinity purification
• Form/Format: In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 1.1mg/ml (varies by lot)
• Sequence Length: 412

• Applicable Applications for anti-DOC2B antibody: Immunohistochemistry (IHC)
• Application Notes: IF: 1: 20-100
• Immunogen: Synthetic peptide of human DOC2B
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 47015(DAGLB Antibody) at dilution 1/20. (Original magnification: 200))

Related Product Information for anti-DOC2B antibody

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells.

Product Categories/Family for anti-DOC2B antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 295054132
• NCBI GeneID: 8447
• NCBI Accession #: NP_003576
• NCBI GenBank Nucleotide #: NM_003585.4
• UniProt Accession #: Q14184
• Molecular Weight: 45,949 Da
• NCBI Official Full Name: double C2-like domain-containing protein beta
• NCBI Official Synonym Full Names: double C2 domain beta
• NCBI Official Symbol: DOC2B
• NCBI Official Synonym Symbols: DOC2BL
• NCBI Protein Information: double C2-like domain-containing protein beta
• UniProt Protein Name: Double C2-like domain-containing protein beta
• Protein Family: Double C2-like domain-containing protein
• UniProt Gene Name: DOC2B
• UniProt Synonym Gene Names: DOC2BL; Doc2-beta

NCBI Description

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells. [provided by RefSeq, Jul 2008]

Uniprot Description

Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes ().