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Western Blot (WB) (Western blot analysis of JAG1 expression in HepG2 cell lysate.)

Rabbit anti-Human JAG1 Polyclonal Antibody | anti-JAG1 antibody

Anti-JAG1 Rabbit pAb

Gene Names
JAG1; AGS; AHD; AWS; HJ1; AGS1; CD339; JAGL1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
JAG1; Polyclonal Antibody; Anti-JAG1 Rabbit pAb; AGS; AHD; Alagille syndrome; CD339 antigen; HJ1; Jagged1; JAGL1; Jagged; Jagged 1; Protein jagged-1; AWS; CD339; Soluble protein jagged; anti-JAG1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
JAG1 Antibody detects endogenous levels of JAG1
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1218
Applicable Applications for anti-JAG1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
A synthesized peptide derived from human JAG1
Subcellular Location
Chromosome
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of JAG1 expression in HepG2 cell lysate.)

Western Blot (WB) (Western blot analysis of JAG1 expression in HepG2 cell lysate.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human kidney, using JAG1 Antibody.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human kidney, using JAG1 Antibody.)
Related Product Information for anti-JAG1 antibody
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
182
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
180kDa
NCBI Official Full Name
protein jagged-1
NCBI Official Synonym Full Names
jagged 1
NCBI Official Symbol
JAG1
NCBI Official Synonym Symbols
AGS; AHD; AWS; HJ1; AGS1; CD339; JAGL1
NCBI Protein Information
protein jagged-1
UniProt Protein Name
Protein jagged-1
Protein Family
UniProt Gene Name
JAG1
UniProt Synonym Gene Names
JAGL1; Jagged1; hJ1

NCBI Description

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]

Uniprot Description

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (). Enhances fibroblast growth factor-induced angiogenesis (in vitro).

Research Articles on JAG1

Similar Products

Product Notes

The JAG1 jag1 (Catalog #AAA4750453) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-JAG1 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's JAG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the JAG1 jag1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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