Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IRGC Polyclonal Antibody at dilution of 1:30(×200))
Rabbit anti-Human, Rat IRGC Polyclonal Antibody | anti-IRGC antibody
IRGC Polyclonal Antibody
Gene Names
IRGC; IFGGE; IRGC1; Iigp5; CINEMA; R30953_1
Reactivity
Human, Rat
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
IRGC; Polyclonal Antibody; IRGC Polyclonal Antibody; F630044M05Rik; Gm1102; Gm474; IIGP5; Immunity-related GTPase cinema 1; Interferon-inducible GTPase 5; IRGC1; RGD1311107; anti-IRGC antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.78mg/mL (varies by lot)
Sequence Length
463
Applicable Applications for anti-IRGC antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:30-1:150
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Synthetic peptide of human IRGC
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IRGC Polyclonal Antibody at dilution of 1:30(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IRGC Polyclonal Antibody at dilution of 1:30(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using IRGC Polyclonal Antibody at dilution of 1:30(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using IRGC Polyclonal Antibody at dilution of 1:30(×200))
Related Product Information for anti-IRGC antibody
Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
Product Categories/Family for anti-IRGC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
interferon-inducible GTPase 5
NCBI Official Synonym Full Names
immunity related GTPase cinema
NCBI Official Symbol
IRGC
NCBI Official Synonym Symbols
IFGGE; IRGC1; Iigp5; CINEMA; R30953_1
NCBI Protein Information
interferon-inducible GTPase 5
UniProt Protein Name
Interferon-inducible GTPase 5
Protein Family
UniProt Gene Name
IRGC
UniProt Synonym Gene Names
IIGP5; IRGC1
UniProt Entry Name
IIGP5_HUMAN
Uniprot Description
IRGC: Belongs to the interferon-inducible GTPase family.
Protein type: Hydrolase; EC 3.6.5.-
Chromosomal Location of Human Ortholog: 19q13.31
Cellular Component: membrane
Molecular Function: GTP binding; hydrolase activity
Biological Process: metabolic process
Research Articles on IRGC
Similar Products
Product Notes
The IRGC irgc (Catalog #AAA2560016) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IRGC Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IRGC can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:30-1:150 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the IRGC irgc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRGC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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