Western Blot (WB)
(Western blot analysis of SGK1 expression in A431 cell lysate.)
Rabbit anti-Human IRAK3 Polyclonal Antibody | anti-IRAK3 antibody
Anti-IRAK3 Rabbit pAb
Gene Names
IRAK3; ASRT5; IRAKM
Reactivity
Human
Applications
Western Blot, Immunoprecipitation
Purity
Affinity Chromatography
Synonyms
IRAK3; Polyclonal Antibody; Anti-IRAK3 Rabbit pAb; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; Interleukin-1 receptor-associated kinase 3; interleukin-1 receptor-associated kinase M; IRAK-3; IRAK-M; IRAKM; anti-IRAK3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
IRAK3 Antibody detects endogenous levels of IRAK3
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
535
Applicable Applications for anti-IRAK3 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
WB: 1:500-1:2000
IP: 1:10
IP: 1:10
Immunogen
A synthesized peptide derived from human IRAK3
Subcellular Location
Cell membrane; Multi-pass membrane protein
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Western Blot (WB)
(Western blot analysis of SGK1 expression in A431 cell lysate.)
Western Blot (WB)
(Western blot analysis of SGK1 expression in A431 cell lysate.)
Related Product Information for anti-IRAK3 antibody
IRAK3 a TKL kinase of the IRAK family. The interleukin-1 receptor-associated kinases are important mediators in the signal transduction of Toll-like receptor and IL1R family members, collectively referred to as TIRs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68kDa
NCBI Official Full Name
interleukin-1 receptor-associated kinase 3 isoform b
NCBI Official Synonym Full Names
interleukin 1 receptor associated kinase 3
NCBI Official Symbol
IRAK3
NCBI Official Synonym Symbols
ASRT5; IRAKM
NCBI Protein Information
interleukin-1 receptor-associated kinase 3
UniProt Protein Name
Interleukin-1 receptor-associated kinase 3
Protein Family
UniProt Gene Name
IRAK3
UniProt Synonym Gene Names
IRAK-3; IRAK-M
NCBI Description
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Uniprot Description
Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Research Articles on IRAK3
Similar Products
Product Notes
The IRAK3 irak3 (Catalog #AAA4750401) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IRAK3 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IRAK3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB: 1:500-1:2000 IP: 1:10. Researchers should empirically determine the suitability of the IRAK3 irak3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRAK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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