Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Mouse lung tissue Amount of lysate: 40ug per lane Primary antibody: 1/850 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Rabbit anti-Human, Mouse IQGAP3 Polyclonal Antibody | anti-IQGAP3 antibody
IQGAP3 Antibody
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Antigen affinity purification.
Synonyms
IQGAP3; Polyclonal Antibody; IQGAP3 Antibody; IQGA3; MGC10170; anti-IQGAP3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total IQGAP3 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.7 mg/ml (varies by lot)
Sequence Length
1631
Applicable Applications for anti-IQGAP3 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:200-1:1000
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to a region derived from internal residues of human IQ motif containing GTPase activating protein 3
Target Name
IQGAP3
Preparation and Storage
Store at -20 degree C
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Mouse lung tissue Amount of lysate: 40ug per lane Primary antibody: 1/850 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Testing Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Mouse lung tissue Amount of lysate: 40ug per lane Primary antibody: 1/850 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Related Product Information for anti-IQGAP3 antibody
IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Product Categories/Family for anti-IQGAP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
184,699 Da
NCBI Official Full Name
ras GTPase-activating-like protein IQGAP3
NCBI Official Synonym Full Names
IQ motif containing GTPase activating protein 3
NCBI Official Symbol
IQGAP3
NCBI Protein Information
ras GTPase-activating-like protein IQGAP3
UniProt Protein Name
Ras GTPase-activating-like protein IQGAP3
Protein Family
UniProt Gene Name
IQGAP3
UniProt Entry Name
IQGA3_HUMAN
Uniprot Description
IQGAP3:
Protein type: Motility/polarity/chemotaxis; GAPs, Ras; GAPs
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: cytoplasm; intercellular junction; lateral plasma membrane
Molecular Function: calmodulin binding; Rho GTPase binding
Biological Process: activation of MAPK activity; Ras protein signal transduction; positive regulation of mammary gland epithelial cell proliferation; regulation of cell size; G1/S transition of mitotic cell cycle
Research Articles on IQGAP3
Similar Products
Product Notes
The IQGAP3 iqgap3 (Catalog #AAA9404449) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IQGAP3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IQGAP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:200-1:1000. Researchers should empirically determine the suitability of the IQGAP3 iqgap3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IQGAP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
