Western Blot (WB)
(INTS1 Antibody western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the INTS1 antibody detected the INTS1 protein (arrow).)
Rabbit INTS1 Polyclonal Antibody | anti-INTS1 antibody
INTS1 Antibody (N-term)
Western Blot (WB)
(INTS1 Antibody western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the INTS1 antibody detected the INTS1 protein (arrow).)
Western Blot (WB)
(INTS1 Antibody western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the INTS1 antibody detected the INTS1 protein (arrow).)
associates with the C-terminal domain of RNA polymerase II large
subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of
small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690)
(Baillat et al., 2005 [PubMed 16239144]).
Baillat, D., et al. Cell 123(2):265-276(2005)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
NCBI and Uniprot Product Information
NCBI Description
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Uniprot Description
INTS1: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Belongs to the Integrator subunit 1 family.
Protein type: RNA processing; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7p22.3
Cellular Component: nuclear membrane; membrane; integral to membrane; integrator complex
Biological Process: snRNA processing; negative regulation of caspase activity; inner cell mass cell proliferation
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Product Notes
The INTS1 ints1 (Catalog #AAA9213288) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 113-142. The INTS1 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's INTS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the INTS1 ints1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INTS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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