Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Interleukin 1 Receptor Associated Kinase 2 (IRAK2) Polyclonal Antibody | anti-IRAK2 antibody
Polyclonal Antibody to Interleukin 1 Receptor Associated Kinase 2 (IRAK2)
MGHHHHHHSGSEF-DQ SHRISEGTFA DIYQGQRNGV AFAFKKLREVAGSSPGSMDR FLQAEMQLCL RCCHANVLPL LGFCTGRQFH SLIYPYMANG SLHDRLWAQG NSDMLPWPQR ASICSGLLLA VEHLHSLDII HSNVKSANVL LDQHLNPKLA HPVAHPHPDN KKTKYTVMRT HLFQASAAYL PEHFIRVGQL TKQVDIFSCG IVLAEVLTGI PAMDKDRSPV YLKDLLLSEI PNSTSSVCSR KTSMGKAVVK EICQRHVE
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
NCBI and Uniprot Product Information
Uniprot Description
IRAK2: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1. Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Protein type: IRAK family; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; TKL group
Chromosomal Location of Human Ortholog: 6 E3|6 52.82 cM
Cellular Component: cytoplasm; nucleus
Molecular Function: ATP binding; nucleotide binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity
Biological Process: activation of NF-kappaB-inducing kinase; I-kappaB kinase/NF-kappaB signaling; inflammatory response; lipopolysaccharide-mediated signaling pathway; MyD88-dependent toll-like receptor signaling pathway; negative regulation of NF-kappaB transcription factor activity; negative regulation of transcription factor activity; positive regulation of NF-kappaB transcription factor activity; protein amino acid phosphorylation; protein autophosphorylation; regulation of apoptosis; regulation of cytokine-mediated signaling pathway; signal transduction; toll-like receptor signaling pathway
Research Articles on IRAK2
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Product Notes
The IRAK2 irak2 (Catalog #AAA2001563) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Interleukin 1 Receptor Associated Kinase 2 (IRAK2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Interleukin 1 Receptor Associated Kinase 2 (IRAK2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the IRAK2 irak2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-DQ SHRISEGTFA DIYQGQRNGV AFAFKKLREV AGSSPGSMDR FLQAEMQLCL RCCHANVLPL LGFCTGRQFH SLIYPYMANG SLHDRLWAQG NSDMLPWPQR ASICSGLLLA VEHLHSLDII HSNVKSANVL LDQHLNPKLA HPVAHPHPDN KKTKYTVMRT HLFQASAAYL PEHFIRVGQL TKQVDIFSCG IVLAEVLTGI PAMDKDRSPV YLKDLLLSEI PNSTSSVCSR KTSMGKAVVK EICQRHVE. It is sometimes possible for the material contained within the vial of "Interleukin 1 Receptor Associated Kinase 2 (IRAK2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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