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Western Blot (WB) (Western blot analysis of Interferon beta expression in HeLa cell lysate.)

Rabbit anti-Human Interferon beta Polyclonal Antibody | anti-IFNB antibody

Anti-Interferon beta Rabbit pAb

Gene Names
IFNB1; IFB; IFF; IFNB; IFN-beta
Reactivity
Human
Applications
Western Blot, Immunoprecipitation
Purity
Affinity Chromatography
Synonyms
Interferon beta; Polyclonal Antibody; Anti-Interferon beta Rabbit pAb; IFN-beta; IFNbeta; Fibroblast interferon; IFB; anti-IFNB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Interferon beta Antibody detects endogenous levels of total Interferon beta
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
187
Applicable Applications for anti-IFNB antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
WB: 1:500-1:2000
IP: 1:50
Immunogen
A synthesized peptide derived from human Interferon beta
Subcellular Location
Secreted
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of Interferon beta expression in HeLa cell lysate.)

Western Blot (WB) (Western blot analysis of Interferon beta expression in HeLa cell lysate.)
Related Product Information for anti-IFNB antibody
The type I interferon (IFN) family includes IFN-beta1 and IFN-alpha1 through IFN-alpha13 in humans and IFN-alpha1 through IFN-alpha14 in mice. Type I IFN is produced following detection of pathogen-associated molecular patterns (PAMPs) and is important for induction of antiviral genes, activation of dendritic cells, and initiation of adaptive immunity. Has antiviral, antibacterial and anticancer activities.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22kDa
NCBI Official Full Name
interferon beta
NCBI Official Synonym Full Names
interferon beta 1
NCBI Official Symbol
IFNB1
NCBI Official Synonym Symbols
IFB; IFF; IFNB; IFN-beta
NCBI Protein Information
interferon beta
UniProt Protein Name
Interferon beta
Protein Family
UniProt Gene Name
IFNB1
UniProt Synonym Gene Names
IFB; IFNB; IFN-beta

NCBI Description

This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]

Uniprot Description

Has antiviral, antibacterial and anticancer activities.

Research Articles on IFNB

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Product Notes

The IFNB ifnb1 (Catalog #AAA4750726) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Interferon beta Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Interferon beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB: 1:500-1:2000 IP: 1:50. Researchers should empirically determine the suitability of the IFNB ifnb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interferon beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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